Results 171 to 180 of about 10,899,927 (248)

Mechanistic insights into circularization via <i>Anabaena</i> group I intron-based scarless circular RNA. [PDF]

Mol Ther Nucleic Acids
Fan B, Liu S, Xu Y, Ma X, Qi W, Miao L, Liu L, Du S, Lin J.   +8 more
europepmc   +1 more source

ECCFP: A consecutive full pass‐based bioinformatic analysis for eccDNA identification from long‐read sequencing data

iMetaOmics, EarlyView.
A new bioinformatics pipeline called ECCFP has been developed to improve the detection of extrachromosomal circular DNA (eccDNA) from long‐read sequencing data. ECCFP uses all consecutive full passes from individual reads for candidate eccDNA identification and consolidates candidate eccDNAs to generate accurate unique eccDNA.
Wang Li, Biyuan Miao, Jun Zhang, Qingsong Zeng, Tangxuan Zhang, Zetong Wu, Yusheng Song, Mengting Li, Lilu Guo, Juan Luo, Jingxiang Xu, Tianliang Liu, Shifu Chen, Jia Gu, Shaogui Wan   +14 more
wiley   +1 more source

Operational burden and fragmented implementation in CAR T-cell therapy: Insights from a multinational survey by the GoCART Coalition and the JACIE Quality Managers Committee. [PDF]

Hemasphere
van Sinderen N, Dolva J, Riillo C, Espada R, Scheid C, van Dorp S, Nijziel M, Jak M, Malard F, Chabannon C, Egan A, Bonini C, Delgado J, Dreyling M, Ruggeri A, Subklewe M, Sureda A, Cabrerizo Y, Yakoub-Agha I, Rintala T, Manson L, Anderson L, Urbain O, Luke R, Brandt Kristensen L, Emmett A, Kuball J.   +26 more
europepmc   +1 more source

Decoding temporal miRNA signatures of semen under in vitro exposure for forensic time since deposition estimation using machine learning‐driven modeling

Interdisciplinary Medicine, EarlyView.
This study develops a novel miRNA‐based framework for estimating the time since deposition of semen stains, combining small RNA sequencing with machine learning. Time‐dependent miRNA modules were identified using Mfuzz clustering and WGCNA, followed by a multi‐stage feature selection pipeline that reduced 261 candidate miRNAs to a minimal 7‐miRNA panel.
Meiming Cai, Qiong Lan, Tong Xie, Qinglin Liu, Ming Zhao, Xiaolian Wu, Xin Shi, Ruonan Shen, Yiman Wu, Chen Mao, Bin Cong, Bofeng Zhu   +11 more
wiley   +1 more source

Single-cell RNA sequencing reveals immune cell dysfunction and rewired interaction networks in the peripheral blood of active tuberculosis patients. [PDF]

BMC Immunol
Wei Y, Pan H, Lu F, Deng X, Wang J.
europepmc   +1 more source

Unravelling the Major Cardiovascular Risks of Systemic Psoriasis Medications: A Literature Systematic Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Psoriasis is a chronic inflammatory dermatological condition associated with an elevated risk of cardiovascular events (CVEs). Systemic therapies have transformed disease management, but their cardiovascular (CV) safety profiles remain incompletely understood and inconsistently reported.
Mai Thi Hoai Son, Yves Julien Mbama Biloa, Pauline Gouttefarde, Thomas Franck, Gilles Cizeron, Mathieu Oriol, François Maccari, Elisa Cinotti, Beatrice Trombert‐Paviot, Bienvenu Bongue, Jean‐Luc Perrot   +10 more
wiley   +1 more source

Development and comprehensive evaluation of scarless circularization systems for circular RNA therapeutics. [PDF]

Mol Ther Nucleic Acids
Chen L, Song L, Yang J, Li T, Ju R, Sun C, Xie Z.   +6 more
europepmc   +1 more source

Compliance of Dermatology Screening Visits Among Patients With Skin Cancer‐Predisposing Pathogenic Variants

JEADV Clinical Practice, EarlyView.
Patients with genetic variants that increase skin cancer risk are recommended to undergo regular dermatology screenings per National Comprehensive Cancer Network guidelines, but compliance is uncertain. In a retrospective study of 230 patients with such variants, compliance with screening visits significantly improved after visiting a Hereditary Cancer
Stephen J. Gadomski, Kevin S. Hughes, Jihad S. Obeid, Courtney Rowley, Graciela De Jesús   +4 more
wiley   +1 more source

Coronary artery bypass grafting in patients with hematological neoplasms. [PDF]

Front Cardiovasc Med
Zhang L, Zhang S, Jiang H, Liu J, Gao Q, Lian B, Liu Z, Shi Y.   +7 more
europepmc   +1 more source

Robotic arm‐assisted total knee arthroplasty reduces postoperative inflammatory response and blood loss compared to manual total knee arthroplasty: A matched‐pairs analysis of 688 patients

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Robotic arm‐assisted total knee arthroplasty (raTKA) has demonstrated several advantages over manual TKA (mTKA), including enhanced early recovery. Reduced soft tissue trauma and avoidance of femoral intramedullary canal opening have been hypothesised to lower the systemic inflammatory response.
Dirk Müller, Igor Lazic, Benjamin Schloßmacher, Vincent Lallinger, Michael T. Hirschmann, Rüdiger von Eisenhart‐Rothe, Florian Pohlig   +6 more
wiley   +1 more source