Results 181 to 190 of about 10,899,927 (248)

Identification of inducible HIV reservoirs in tonsillar, intestinal and cervical tissue models of HIV latency. [PDF]

Nat Commun
Gallego-Cortés A, Sánchez-Gaona N, Mancebo-Pérez C, Ruiz-Isant O, Benítez-Martínez A, Landolfi S, Castellví J, Pumarola F, Ortiz N, Llano I, Lorente J, Mañalich-Barrachina L, Prado JG, Martín-Gayo E, Falcó V, Genescà M, Buzon MJ.   +16 more
europepmc   +1 more source

Improved COI taxonomic assignment workflow enhances detection of invertebrates in environmental DNA

Limnology and Oceanography: Methods, EarlyView.
Abstract Environmental DNA (eDNA) metabarcoding is an increasingly popular and powerful tool in ecology, offering a non‐invasive method to assess biodiversity and monitor ecosystem health across diverse environments. While the mitochondrial cytochrome c oxidase subunit I (COI) gene is one of the most widely used markers for studying eukaryotic ...
Yuanyu Cheng, David Walsh, Joanna Gauthier, Marie‐Eve Monchamp, Daniel T. Selbie, Irene Gregory‐Eaves   +5 more
wiley   +1 more source

Enhancing radial strength and expansion uniformity of iron-based vascular scaffolds: a numerical and experimental investigation on topological optimization. [PDF]

Front Bioeng Biotechnol
Qiu J, Tang L, Fu W, Qin L, Zhang D, Wang S, Song J.   +6 more
europepmc   +1 more source

Next Generation 7 Tesla Arterial Spin Labeling With Rotated Spiral Acquisition Enables Mesoscale Resolution in 3D Brain Perfusion and Functional MRI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To achieve high resolution (≤ 1 mm isotropic) whole‐brain perfusion imaging at 7 T with next generation ASL pulse sequence, reconstruction algorithm, and MRI hardware. Methods We capitalized on three major innovations: (1) FLASH‐based pseudo‐Continuous ASL (pCASL) sequence with rotated golden‐angle stack‐of‐spirals (rGA‐SoS) sampling; (
Chenyang Zhao, Fanhua Guo, Zidong Yang, Xingfeng Shao, Samantha J. Ma, Alexander J. S. Beckett, An T. Vu, David A. Feinberg, Danny J. J. Wang   +8 more
wiley   +1 more source

Single-molecule tracking of DNMT1 in living cells reveals its cell cycle dynamics and its redistribution upon drug treatment. [PDF]

Nucleic Acids Res
Lee ES, Tommer ER, Rothman PB, Middleton SV, Youmans DT, Cech TR.   +5 more
europepmc   +1 more source

C/EBPα is Essential for Gonadal but Not Inguinal White Adipose Tissue Formation in Mice

Obesity, EarlyView.
Human genetics has linked the gene CEBPA to waist to hip ratio and adipose distribution. We generated mice with AdipoQ‐Cre driven deletion of Cebpa and found these mice to have a specific reduction in gonadal white adipose tissue and myriad other metabolic phenotypes.
Krista Y. Hu, Yu‐Lin Ma, Esme A. Dodge, Olivia A. B. Maguire, Caio V. Matias, Ryan P. Barney, Hector S. Himede, Juliana Gomez Pardo, Miriam Cepeda, Scott M. Gordon, Robert C. Bauer   +10 more
wiley   +1 more source

ePerturbDB: enhancer's experimental perturbation database. [PDF]

Database (Oxford)
Maurya S, Sharma J, Mandoli A, Kumar V.
europepmc   +1 more source

Uncovering the Genetic Landscape of Spinal Dysraphism: A Retrospective Analysis of 150 Fetal Cases

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Spinal dysraphism (SD) results from incomplete neural tube closure and encompasses a heterogeneous group of congenital anomalies with genetic and environmental etiologies. Although genetic contributions are recognized, causative variants remain insufficiently defined, and the clinical implications of extended genetic testing on ...
I. Bedei, A. Feresin, R. Zemet, D. Berner, D. Polidori, K. Fröbius, A. Skakkebæk, R. Axt‐Fliedner, M. Shoukier, C. Keil   +9 more
wiley   +1 more source

Antigenic-Specificity and Cytokine Profile of the T-Cell Response to Human Cytomegalovirus in Transplant Recipients. [PDF]

Pathogens
Zavaglio F, Zelini P, Cera A, d'Angelo P, Gregorini M, Rampino T, Del Frate L, Meloni F, Borsani O, Pellegrini C, Baldanti F, Lilleri D.   +11 more
europepmc   +1 more source

Biomolecular Interaction Prediction in the Pre‐ and Post‐AlphaFold Era: The 8th CAPRI Evaluation

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT We report on the 8th CAPRI Evaluation period, capturing the assessment of CAPRI Rounds 47 to 55 (excluding the CASP and COVID‐related Rounds), which have witnessed the transition to AI‐driven prediction tools such as AlphaFold and related alternatives. The prediction Rounds in this evaluation are characterized by a high level of difficulty due
Marc F. Lensink, Nessim Raouraoua, Guillaume Brysbaert, Sameer Velankar, Shoshana J. Wodak, Alexandre M. J. J. Bonvin   +5 more
wiley   +1 more source