Results 51 to 60 of about 18,829 (175)

In silico modelling of CD8 T cell immune response links genetic regulation to population dynamics

open access: yesImmunoInformatics
The CD8 T cell immune response operates at multiple temporal and spatial scales, including all the early complex biochemical and biomechanical processes, up to long term cell population behavior.In order to model this response, we devised a multiscale ...
Thi Nhu Thao Nguyen   +5 more
doaj   +1 more source

Asymptotic Control for a Class of Piecewise Deterministic Markov Processes Associated to Temperate Viruses

open access: yes, 2015
We aim at characterizing the asymptotic behavior of value functions in the control of piece-wise deterministic Markov processes (PDMP) of switch type under nonexpansive assumptions.
Goreac, Dan
core   +4 more sources

Reinforcement Learning for Jump‐Diffusions, With Financial Applications

open access: yesMathematical Finance, EarlyView.
ABSTRACT We study continuous‐time reinforcement learning (RL) for stochastic control in which system dynamics are governed by jump‐diffusion processes. We formulate an entropy‐regularized exploratory control problem with stochastic policies to capture the exploration–exploitation balance essential for RL.
Xuefeng Gao, Lingfei Li, Xun Yu Zhou
wiley   +1 more source

Viability, Invariance and Reachability for Controlled Piecewise Deterministic Markov Processes Associated to Gene Networks

open access: yes, 2010
We aim at characterizing viability, invariance and some reachability properties of controlled piecewise deterministic Markov processes (PDMPs). Using analytical methods from the theory of viscosity solutions, we establish criteria for viability and ...
Goreac, D.
core   +4 more sources

Navigating Supply Shocks: Sector Resilience and Production Prices Through Stochastic Input–Output Modeling

open access: yesMathematical Finance, EarlyView.
ABSTRACT This study develops a novel multivariate stochastic framework for assessing systemic risks, such as climate and nature‐related shocks, within production or financial networks. By embedding a linear stochastic fluid network, interpretable as a generalized vector Ornstein–Uhlenbeck process, into the production network of interdependent ...
Giovanni Amici   +3 more
wiley   +1 more source

Viscosity solutions of two classes of coupled Hamilton-Jacobi-Bellman equations

open access: yesJournal of Inequalities and Applications, 2001
This paper studies viscosity solutions of two sets of linearly coupled Hamilton-Jacobi-Bellman (HJB) equations (one for finite horizon and the other one for infinite horizon) which arise in the optimal control of nonlinear piecewise deterministic ...
Başar Tamer, Xiao Mingqing
doaj  

Intrinsic noise in systems with switching environments

open access: yes, 2016
We study individual-based dynamics in finite populations, subject to randomly switching environmental conditions. These are inspired by models in which genes transition between on and off states, regulating underlying protein dynamics. Similarly switches
Galla, Tobias   +3 more
core   +1 more source

On time reversal of piecewise deterministic Markov processes

open access: yesElectronic Journal of Probability, 2013
We study the time reversal of a general PDMP. The time reversed process is defined as $X_{(T-t)-}$, where $T$ is some given time and $X_t$ is a stationary PDMP. We obtain the parameters of the reversed process, like the jump intensity and the jump measure.
Löpker, Andreas, Palmowski, Zbigniew
openaire   +4 more sources

Online Jump and Kink Detection in Segmented Linear Regression: Statistical Optimality Meets Computational Efficiency

open access: yesJournal of Time Series Analysis, Volume 47, Issue 3, Page 727-748, May 2026.
ABSTRACT We consider the problem of sequential (online) estimation of a single change point in a piecewise linear regression model under a Gaussian setup. We demonstrate that certain CUSUM‐type statistics attain the minimax optimal rates for localizing the change point.
Annika Hüselitz, Housen Li, Axel Munk
wiley   +1 more source

Causal Inference for Geostatistical Data Using an INLA‐based Spatial Propensity Score

open access: yesEnvironmetrics, Volume 37, Issue 3, April 2026.
ABSTRACT In this paper, we propose a Bayesian approach for spatial causal inference based on combining spatial propensity scoring with Integrated Nested Laplace Approximation. The method models both local and spillover exposure effects via multiple likelihoods and treats counterfactuals as missing data, allowing inference also for non‐Gaussian outcomes.
Chiara Di Maria   +3 more
wiley   +1 more source

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