Results 31 to 40 of about 2,091,028 (234)

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Structure‐Polarization‐Function Relationship in Oxide Perovskite for Solar‐To‐Fuel Conversion Challenge

EcoEnergy, EarlyView.
Oxide perovskites (ABO3) have emerged as paradigm‐shifting materials for solar energy conversion, uniquely combining ferroelectric polarization, piezoelectric response, and tunable optoelectronic properties. This review comprehensively examines how controlled structural distortions generate built‐in electric fields that overcome ultrafast charge ...
Xu Qian, Xinyu Li, Yihang Yu, Rayees Ahmad Rather, Christophe Colbeau‐Justin, Jingwei Li, Mohamed Nawfal Ghazzal   +6 more
wiley   +1 more source

Frantz tumor: analysis of diagnostic and therapeutic aspects in a series of 21 cases [PDF]

Batna Journal of Medical Sciences
Solid pseudopapillary neoplasms of the pancreas (Frantz tumor) are described as rare and have a low malignant potential. The objective of this study is to report the clinical and therapeutic characteristics, as well as the short- and long-term follow ...
Mohamed Abdelmalek HAFTARI, Ghozlene BAHBOUH, Adem Anis DAÏF, Imen HAROUN, Sabrina BENAMEUR, Zakia HATTOU, Ihcene Hatem BOUTEKEDJIRET, Mohand KHELOUFI, Zaki BOUDIAF, Ahlam ALGHAZALI, Karim CHERCHAR, Kamel BENTABAK   +11 more
doaj   +1 more source

Second Breast‐Conserving Treatment for Ipsilateral Breast Tumor Recurrence: A Review of Patient Selection, Reirradiation Techniques, and Clinical Outcomes

International Journal of Cancer, EarlyView.
ABSTRACT Local recurrence after primary breast cancer treatment remains a complex clinical scenario in patients previously treated with breast‐conserving therapy and radiotherapy. For decades, salvage mastectomy was considered the standard treatment for ipsilateral breast tumor recurrence, largely because of concerns about local control after repeat ...
Cezara Cheptea, Youlia Kirova, Radu Iulian Mitrica, Mihaela Badea, Pierre Loap   +4 more
wiley   +1 more source

Corrosion Analysis of Rapidly Solidified and Subsequently Aged Al‐Ni and Al‐Fe‐Ni Alloys

Materials and Corrosion, EarlyView.
Fe addition modifies intermetallic phase chemistry and microgalvanic interactions in Al‐Ni alloys, shifting corrosion from generalized dissolution to localized attack. ABSTRACT This study investigates the influence of Fe addition and heat treatment on the corrosion behavior of Al–5 wt.%Ni and Al–2 wt.%Fe–1.5 wt.%Ni alloys, with particular emphasis on ...
Jaderson Rodrigo da Silva Leal, Virginie Roche, Margarita Diaz‐Ramos, Alberto Moreira Jorge Junior, José Eduardo Spinelli   +4 more
wiley   +1 more source

Silencing of the Charcot–Marie–Tooth associated MTMR2 gene decreases proliferation and enhances cell death in primary cultures of Schwann cells

Neurobiology of Disease, 2007
Loss of function of the myotubularin (MTM)-related protein 2 (MTMR2) in Schwann cells causes Charcot–Marie–Tooth disease type 4B1, a severe demyelinating neuropathy, but the consequences of MTMR2 disruption in Schwann cells are unknown.
Alexandre Chojnowski, Nicole Ravisé, Corinne Bachelin, Christel Depienne, Merle Ruberg, Bernard Brugg, Jocelyn Laporte, Anne Baron-Van Evercooren, Eric LeGuern   +8 more
doaj   +1 more source

Real‐World HRR Testing Pathways and Patterns of Detected Alterations in Prostate Cancer From the Multinational ARON‐3 Study

The Prostate, EarlyView.
ABSTRACT Background Homologous recombination repair (HRR) testing is increasingly relevant in prostate cancer because it identifies patients who may benefit from biomarker‐guided treatment strategies, including poly(ADP‐ribose) polymerase inhibitors (PARPi).
Lorena Incorvaia, Veronica Mollica, Ondřej Fiala, Kazutoshi Fujita, Yüksel Ürün, Bohuslav Melichar, Javier Molina‐Cerrillo, Teresa Alonso‐Gordoa, Umberto Basso, Maria T. Bourlon, Emmanuel Seront, Ugo De Giorgi, Maria José Juan Fita, Pasquale Rescigno, Tarek Taha, Fernando C. Maluf, Alexandr Poprach, Simona De Summa, Tomas Buchler, Luca Galli, Jindrich Kopecky, Gaetano Aurilio, Jakub Kucharz, Carlo Messina, Gabriel Berlingieri Polho, Sarah Scagliarini, Francesco Grillone, Diogo Assed Bastos, Luigi Formisano, Gian Paolo Spinelli, Alessandra Mosca, Alessandro Rizzo, Aristotelis Bamias, Fernando Sabino Marques Monteiro, Andrey Soares, Francesco Massari, Andrew J. Armstrong, Matteo Santoni   +37 more
wiley   +1 more source

A Biomimetic Breast Tumor‐On‐Chip Platform Reveals Mesenchymal Marker Upregulation Following Gold Nanorod Photothermal Therapy

Small, EarlyView.
A biomimetic microfluidic tumor‐on‐chip platform was designed to uncover subtype‐dependent responses to nanoparticle‐mediated photothermal therapy in breast cancer spheroids. The platform establishes a physiologically relevant and controllable 3D system for precision evaluation of nanophotothermal cancer therapies.
Camila A. Salvego, Hasti Honari, Anastasiia Dubrova, Stéphanie Descroix, Martha S. Ribeiro, Aurore V. Walle, Claire Wilhelm   +6 more
wiley   +1 more source

Nitric oxide-sphingolipid interplays in plant signalling: a new enigma from the Sphinx?

Frontiers in Plant Science, 2013
Nitric oxide (NO) emerged as one of the major signalling molecules operating during plant development and plant responses to its environment. Beyond the identification of the direct molecular targets of NO, a series of studies considered its interplay ...
Isabelle eGuillas, Juliette ePuyaubert, Emmanuel eBAUDOUIN   +2 more
doaj   +1 more source

immunoHuMiX: A personalizable gut‐on‐chip model for unraveling human microbiome–immune interactions

VIEW, EarlyView.
The study introduces a personalized gut model that brings together human immune cells and intestinal cells to better mimic how the body interacts with microbes. This system successfully maintained both human cells and a 17‐strain probiotic community, showing consistent immune responses across different donors.
Charlotte De Rudder, Kacy Greenhalgh, Joanna Baginska, Camille Martin‐Gallausiaux, Léa Grandmougin, Rémy Villette, Mara Lucchetti, Bérénice Hansen, Marek Ostaszewski, Viacheslav A. Petrov, Koji Atarashi, Lena Weidert, Audrey Frachet Bour, Dominik Ternes, Javier Ramiro‐Garcia, Antoine Malabirade, Takeshi Tanoue, Marc Mac Giolla Eain, Elisabeth Letellier, Matthew Barrett, Jérôme Lacombe, Frederic Zenhausern, Coralie Guérin, Markus Ollert, Carole Seguin‐Devaux, Kenya Honda, Paul Wilmes   +26 more
wiley   +1 more source