Results 61 to 70 of about 54,448 (306)

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum   +5 more
wiley   +1 more source

Real‐Time 3D Ultrasound Imaging with an Ultra‐Sparse, Low Power Architecture

open access: yesAdvanced Healthcare Materials, EarlyView.
This article presents a novel, ultra‐sparse ultrasound architecture that paves the way for wearable real‐time 3D imaging. By integrating a unique convolutional array with chirped data acquisition, the system achieves high‐resolution volumetric scans at a fraction of the power and hardware complexity.
Colin Marcus   +9 more
wiley   +1 more source

PIEZO channel protein naturally expressed in human breast cancer cell MDA-MB-231 as probed by atomic force microscopy

open access: yesAIP Advances, 2018
Mechanical stimuli drives many physiological processes through mechanically activated channels, and the recent discovery of PIEZO channel has generated great interests in its mechanotransduction.
Yuanqi Weng   +7 more
doaj   +1 more source

Intelligent Acousto‐Electrical Metamaterials (IAM) for Sound Source Detection

open access: yesAdvanced Materials, EarlyView.
Our proposed metamaterial concept enables sound source detection using a single material, in contrast to conventional arrays that require dozens or even hundreds of transducers. We show that the coupled acoustic–vibrational–electrical responses in piezoelectric metamaterials give rise to topology‐governed charge transport, producing distinct voltage ...
Victor Couëdel   +7 more
wiley   +1 more source

Thermomechanics of Picoliter Liquids Encapsulated in Metal Microarchitectures

open access: yesAdvanced Materials, EarlyView.
Picoliter‐scale water is encapsulated inside hollow copper microcylinders through a single‐step localized electrodeposition process. Mechanical testing at room and cryogenic temperatures reveals that incompressible liquid and load‐bearing microscale ice enhance the strength and deformation behavior of the composite structure.
Sung‐Gyu Kang   +15 more
wiley   +1 more source

Sperm Injection at the Para‐Polar Body Site in Piezo‐Intracytoplasmic Sperm Injection Improves Subsequent Early Development of Bovine Embryos

open access: yesReproductive Medicine and Biology
Purpose In piezo‐ICSI, the first polar body (PB) of a metaphase II (MII) oocyte is generally oriented in the 6 or 12 o'clock position relative to sperm injection at 3 o'clock.
Shiori Ashibe   +3 more
doaj   +1 more source

Probing the gating mechanism of the mechanosensitive channel Piezo1 with the small molecule Yoda1

open access: yesNature Communications, 2018
Piezo ion channels transduce mechanical stimuli into biological signals but the underlying mechanism has remained elusive. Here, the authors use the selective agonist Yoda1 to identify molecular determinants of Piezo activation, providing mechanistic ...
Jerome J. Lacroix   +2 more
doaj   +1 more source

An Energy Focusing Flexible and Lightweight Acoustic Metamaterial for Enhanced Ultrasound Power Transfer

open access: yesAdvanced Materials, EarlyView.
A flexible and lightweight acoustic metamaterial composed of air cavities encased in polydimethylsiloxane (PDMS) is introduced to enhance ultrasound power transfer. The metamaterial leverages the strong reflectivity of air cavity boundaries to concentrate incoming ultrasound, thereby improving the performance of piezoelectric energy harvesters ...
Hyung‐Suk Kwon   +4 more
wiley   +1 more source

Activating a Metallization Switch for Record Hydrogen Evolution in Single‐Atom Modified Polar MOF Piezocatalysts

open access: yesAdvanced Materials, EarlyView.
ABSTRACT Piezocatalytic hydrogen evolution enables the conversion of mechanical energy into chemical fuels, but its efficiency is constrained by a trade‐off between piezoelectric polarization and electronic conductivity. Strong piezoelectric polarization is essential for sufficient driving force, yet highly polar materials typically suffer from poor ...
Chongyan Hao   +13 more
wiley   +1 more source

Piezo activity levels need to be tightly regulated to maintain normal morphology and function in pericardial nephrocytes

open access: yesScientific Reports
Due to their position on glomerular capillaries, podocytes are continuously counteracting biomechanical filtration forces. Most therapeutic interventions known to generally slow or prevent the progression of chronic kidney disease appear to lower these ...
Kristina Schulz   +8 more
doaj   +1 more source

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