Results 181 to 190 of about 34,545 (300)

Impact of Highly Effective Modulator Therapy on Olfactory‐Specific Gene Expression in People With Cystic Fibrosis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis is common in people with cystic fibrosis (PwCF). Highly effective modulator therapy (HEMT) has been shown to improve sinonasal outcomes. However, prior studies failed to show improvement in objective olfaction with HEMT, and the impact of HEMT on olfactory‐specific quality of life has yet to be studied ...
Michael R. Xiang, Ankit Chauhan, Gina Hong, Denis Hadjiliadis, Daniel Dorgan, Michael M. Rey, Samantha Kane, James N. Palmer, Nithin D. Adappa, Noam A. Cohen, Michael A. Kohanski, Jennifer E. Douglas   +11 more
wiley   +1 more source

Effect of farrowing room temperature adjustment on total electrical energy consumption and sow and litter performance. [PDF]

Trop Anim Health Prod
Bittencourt JE, Schultz C, Peripolli V, Quirino MW, Foppa L, Corezzolla JL, Lima GFR, Moreira F, Lucia T, da Rosa Ulguim R, Bianchi I.   +10 more
europepmc   +1 more source

Association of DPP4 with esophageal stricture progression and the Hippo‐YAP pathway

Animal Models and Experimental Medicine, EarlyView.
This study establishes a comprehensive translational platform for esophageal stricture (ES) research by integrating a novel rat model with clinically relevant porcine validation. This study identifies DPP4 as a gene of interest associated with ES following endoscopic submucosal dissection, demonstrating that prophylactic DPP4 inhibition attenuates ...
Rui Wu, Chen Wang, Hui‐Min Tao, Jin Huang, Wei‐Qin Li, Zhi‐Ning Fan   +5 more
wiley   +1 more source

Generalizable Strategies for the Synthesis of Cereblon‐Recruiting PROTAC Prodrugs

Angewandte Chemie, EarlyView.
Cereblon‐recruiting PROTACs remain challenging to derivatize for prodrug‐based delivery. In this study, three complementary conjugation strategies enabled the efficient synthesis of cleavable PROTAC prodrugs with tunable release kinetics that can be incorporated into a library of PEGylated constructs and bottlebrush prodrugs.
Aiden X. Wang, Bin Liu, Elise M. Ackerman, Yichen Xiang, Hung V.‐T. Nguyen, Yivan Jiang, Angela N. Koehler, Jeremiah A. Johnson   +7 more
wiley   +2 more sources

Dietary fiber sources affect reproductive and lactation outcomes and colostrum protein concentration in sows. [PDF]

Trop Anim Health Prod
Lopes IMG, Lima MD, Ferreira SV, Oliveira ACR, Andrade BR, Ribeiro RJSF, Silveira NCDS, Souza AC, Dos Santos LLDR, Ramos LA, Silva FCO, Saliba EOS, Fontes DO.   +12 more
europepmc   +1 more source

Arthrogryposis in piglets

Kansas Agricultural Experiment Station Research Reports, 1978
H W Leipold, R Ely, D Schoneweis
openaire   +2 more sources

Syndactyly in pigs. [PDF]

Open Vet J
Fernández-Vásquez JL, Sánchez-Silva S, Portal-Torres J, Zambrano L, Cueva-Rodríguez M.   +4 more
europepmc   +1 more source

Animal stroke models and outcome evaluation: A review

Animal Models and Experimental Medicine, EarlyView.
Rodents are the preeminent stroke model species. Large animal models exist too, but are poorly standardized. Ischemic and hemorrhagic experimental models are available, with the intraluminal filament model being predominant. Outcomes are evaluated via quantifying subjects' sensorimotor impairment, cognitive memory faculties, degree of cellular ...
Solsa Cariba, Helen M. Atkinson, Anthony K. C. Chan   +2 more
wiley   +1 more source

A pantothenic acid deficiency outbreak causing mortality and neuromuscular disorders in newborn and nursery piglets. [PDF]

Porcine Health Manag
Loscertales SI, Romagosa A, Martino L, Cid-Cañete M, Bosco S, Leiva-Forns M, Segalés J.   +6 more
europepmc   +1 more source

Modeling Catheter‐Associated Bladder Mucosal Adhesion and Microtrauma Using a Human Urothelial Microtissue Model

Advanced NanoBiomed Research, EarlyView.
Intermittent catheter use can damage the urinary tract and predispose to infection. We deployed a complex human urothelial model to investigate. Catheter contact induced compressive and shear stress causing umbrella cell disruption, reduced barrier function, inflammation and increased cell adhesion to the catheter surface.
Nazila V. Jafari, Jennifer L. Rohn
wiley   +1 more source