Results 191 to 200 of about 23,307 (292)

Exploring the potential of ucuúba (Virola surinamensis) seed fat

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Ucuúba (Virola surinamensis) fat is an important income source for Amazonian communities. Local businesses typically process whole seeds for fat extraction; however, seed structural integrity may influence extraction efficiency and fat quality.
Juan David Marmolejo Tascón, Eduardo Macedo de Melo, Jane Mara Block, Cristiano José de Andrade, Sandra Regina Salvador Ferreira   +4 more
wiley   +1 more source

Paired DNA and RNA sequencing uncovers common and rare variation regulating human retinal gene expression. [PDF]

Nat Commun
Sampson J, Segrè AV, Bujakowska KM, Clark SJ, Bishop PN, Haynes S, Baralle D, Al-Deek J, Holden S, Anderson B, Hayes A, Kemal RA, Thomas HB, O'Keefe RT, Banka S, Black GC, Sergouniotis PI, Ellingford JM.   +17 more
europepmc   +1 more source

Harnessing plant‐based platform for low‐cost cellulosic sugar recovery from bioenergy crops

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract The price of pure cellulase enzyme for the recovery of fermentable cellulosic sugars is one of the major challenges that limit the commercialization of second‐generation biofuels and bio‐based products. This work shows a means to greatly reduce the cost of cellulases. The abundant capacity of plants to synthesize and hyperaccumulate transgenic
Shraddha Maitra, Kristen Eilts, Raunak Bansal, Stephen P. Long, Vijay Singh   +4 more
wiley   +1 more source

Severe Polypoidal Choroidal Vasculopathy as a Harbinger of Spontaneous Suprachoroidal Hemorrhage. [PDF]

J Vitreoretin Dis
Tao BK, Pereira A, Gemae M, Bakshi N, Tang T, Christakis P, Cruz-Pimentel M, Yan P.   +7 more
europepmc   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Unveiling Raphael's Christ Blessing: Chemical Analysis Reveals Distinctive Underdrawing Techniques and a Rare Early Use of Egyptian Blue in Renaissance Art. [PDF]

ACS Omega
Pozzi F, Ricci C, Morlotti M, Demonte D, Castelli L, Ruberto C, Cucci C, Picollo M, Stefani L, Gargano M.   +9 more
europepmc   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Machine Learning Models of Phase Contrast Images Predict Efficiency of Human Pluripotent Stem Cell Differentiation to Cardiomyocytes

Biotechnology and Bioengineering, EarlyView.
Human pluripotent stem cells were differentiated to cTnT+ cardiomyocytes and imaged throughout the process using phase contrast. We predicted differentiation efficiency (cTnT+ area) from phase contrast and compared model performance with a live‐cell cTnT‐GFP reporter.
Austin K. Feeney, Yaniv Ovadia, Aaron D. Simmons, Christian Elabd, Claire J. Peplinski, Frank Li, Sean P. Palecek   +6 more
wiley   +1 more source

Comparative phenotypic analysis of rhodopsin supports stepwise evolution of dim-light vision in early vertebrates. [PDF]

Mol Biol Evol
Cui Y, Lu X, Wei P, Shuai M, Sun L, Xie Y, Xie Y, Dong R, Shi L, Rossiter SJ, Xu S, Liu Y.   +11 more
europepmc   +1 more source

Real‐Time Biomass Estimation in High‐Density Yeast Fermentations Using Soft Sensor Modeling

Biotechnology and Bioengineering, EarlyView.
Accurate biomass measurements, both offline and online, are essential to improve prediction and control in yeast fermentation. This study develops regression‐based predictive models to correlate offline measurements (Dry Cell Weight and OD600 from a spectrophotometer) with online OD860 probe signals to provide accurate real‐time biomass estimations and
Ana G. Del Hierro, José Luis Checa‐Barrera, Juan A. Moreno‐Cid, Eoin Casey   +3 more
wiley   +1 more source