Results 1 to 10 of about 144,463 (199)

Nonclassic congenital lipoid adrenal hyperplasia diagnosed at 17 months in a Korean boy with normal male genitalia: emphasis on pigmentation as a diagnostic clue [PDF]

open access: diamondAnnals of Pediatric Endocrinology & Metabolism, 2020
Congenital lipoid adrenal hyperplasia (CLAH) is one of the most fatal conditions caused by an abnormality of adrenal and gonadal steroidogenesis. CLAH results from loss-of-function mutations of the steroidogenic acute regulatory (STAR) gene; the disease ...
Hosun Bae   +7 more
doaj   +3 more sources

Morphological Alterations and Increased S100B Expression in Epidermal Langerhans Cells Detected in Skin from Patients with Progressive Vitiligo

open access: yesLife, 2021
The role of Langerhans cells (LCs) in vitiligo pathogenesis remains unclear, with published studies reporting contradictory results regarding the quantity of LCs and no data on the features of LCs in vitiligo.
Fei Yang   +4 more
doaj   +1 more source

Low Temperature Effect on the Endocrine and Circadian Systems of Adult Danio rerio

open access: yesFrontiers in Physiology, 2021
The control of the biological rhythms begins with the activation of photo- and thermosensitive cells located in various organs of the fish such as brain, eye, and skin, but a central clock is still to be identified in teleosts.
Cristhian D. Sua-Cespedes   +8 more
doaj   +1 more source

Herb Sanqi-Derived Compound K Alleviates Oxidative Stress in Cultured Human Melanocytes and Improves Oxidative-Stress-Related Leukoderma in Guinea Pigs

open access: yesCells, 2021
Sanqi, a traditional Chinese herb, is widely used for cardiovascular diseases, and its neuroprotective effects against oxidative stress were recently discovered. The purpose of this study was to investigate whether Sanqi-derived compound K (Sanqi-CK), an
Suwei Tang   +6 more
doaj   +1 more source

In vitro quantification of pigment production and transfer in 2D co-cultures and 3D skin organotypic

open access: yesSTAR Protocols, 2023
Summary: Here, we present a protocol to set up and study 2D keratinocyte-melanocyte co-cultures and 3D full-thickness human skin equivalents. We describe steps for culturing of keratinocyte and melanocyte lines and the establishment of both 2D and 3D co ...
Rachel Phua   +6 more
doaj   +1 more source

CasEcR and CasMIH Genes in the Blue Crab, Callinectes sapidus: A Temporal Evaluation and Melatonin Effects

open access: yesFrontiers in Physiology, 2022
Environmental cues synchronize endogenous rhythms of many physiological processes such as hormone synthesis and secretion. Little is known about the diurnal pattern of hormones and gene expression of the Callinectes sapidus molt cycle.
Daniela Dantas David   +7 more
doaj   +1 more source

The two faces of mast cells in vitiligo pathogenesis

open access: yesExploration of Immunology, 2021
Aim: Previously, we reported increased number of T helper 17 (Th17) cells in vitiligo. However, in our recent study, tryptase and interleukin (IL)17 double positive cells which identified by polyclonal anti-IL17 antibody with specificity for IL17A, B, D,
Ichiro Katayama   +4 more
doaj   +1 more source

Loss of Melanopsin (OPN4) Leads to a Faster Cell Cycle Progression and Growth in Murine Melanocytes

open access: yesCurrent Issues in Molecular Biology, 2021
Skin melanocytes harbor a complex photosensitive system comprised of opsins, which were shown, in recent years, to display light- and thermo-independent functions.
Leonardo Vinícius Monteiro de Assis   +5 more
doaj   +1 more source

A case of hyperpigmentation induced by hydroxychloroquine and quinacrine in a patient with systemic lupus erythematosus and review of the literature

open access: yesInternational Journal of Women's Dermatology, 2020
Hydroxychloroquine (HQ) and quinacrine are widely used antimalarials for systemic lupus erythematosus (SLE) and other autoimmune diseases. We report a case of antimalarial-induced hyperpigmentation in a 57-year old African-American woman. The patient had
Daniel Kwak, Pearl E. Grimes, MD
doaj   +1 more source

Effect of a precision cryotherapy device with temperature adjustability on pigmentation

open access: yesIndian Journal of Dermatology, 2022
Background: Pigmentary skin disorders impair the quality of life, leading to the development of therapeutic modalities. However, these treatments should focus more on effectiveness and safety.
Mi Hee Kwack   +5 more
doaj   +1 more source

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