Results 101 to 110 of about 5,960,249 (275)

Mosaic KRAS Variant as a Cause of Developmental Eye Anomalies in an Individual With EncephaloCranioCutaneous Lipomatosis

Clinical Genetics, EarlyView.
We describe a girl presenting with structural eye anomalies and a constellation of features suggestive of the mosaic RASopathy EncephaloCranioCutaneous Lipomatosis (ECCL). Tissue‐specific investigations identified a mosaic KRAS variant at a mutational hotspot (p.[Ala146Pro]), prompting appropriate tumour surveillance.
Karthikah Jeganathan, Fabiola Ceroni, Samuel J. H. Clokie, Nicole Motton Hill, Manoj Parulekar, Karl Johnson, Lidiya V. Talbot, Dorine A. Bax, Nicola K. Ragge   +8 more
wiley   +1 more source

Reticulate acropigmentation of Kitamura in a case of Gorlin-Goltz syndrome − coincidence or association?

Pigment International
Gorlin-Goltz syndrome also known as nevoid basal cell carcinoma syndrome (NBCCS) is a rare, complex hereditary disorder characterized by phenotypic developmental anomalies and postnatal tumors especially basal cell carcinomas (BCCs) and medulloblastomas.
Roda Laishram, Riti Bhatia, Neirita Hazarika, Madhubari Vathulya, Pakesh Baishya, Amit Saroha   +5 more
doaj   +1 more source

Line-field confocal optical coherence tomography can help differentiating melanoma from pigmented basal cell carcinoma: A case report. [PDF]

Skin Res Technol, 2023
Wolswijk T, Sanak D, Lenoir C, Cinotti E, Tognetti L, Rubegni P, Perez-Anker J, Puig S, Malvehy J, Perrot JL, Mosterd K, Del Marmol V, Suppa M.   +12 more
europepmc   +1 more source

Targeting CKIP‐1 for Disease Therapy: Cellular Functions, Molecular Networks, and Clinical Potential

Cell Proliferation, EarlyView.
CKIP‐1, as a scaffold protein with special structural domains, treats related diseases through multiple emerging targeted technologies.
Xin Huang, Shijie Lv, Lejia Li, Jirong Xie, Zhengguo Cao   +4 more
wiley   +1 more source

A Retrospective Analysis of Pigmented Basal Cell Carcinoma in a Tertiary Care Center. [PDF]

Indian Dermatol Online J, 2022
Sadhasivamohan A, Palaniappan V, Karthikeyan K.   +2 more
europepmc   +1 more source

Methyl 4‐O‐Demethylbarbatate Destabilises HIF‐1α and Enhances Temozolomide Sensitivity in Glioma Cells

Cell Proliferation, EarlyView.
The lichen‐derived metabolite methyl 4‐O‐demethylbarbatate (Me‐4‐O‐DBA) suppresses glioma stemness, motility, and metabolic plasticity through inhibition of HIF‐1α signaling and synergistically enhances temozolomide activity, highlighting a potential strategy to target stemness‐driven therapeutic resistance in glioma.
Rui Zhou, Mücahit Varlı, Rundong Liu, Jieun Yu, Hyung‐Ho Ha, Jae‐Seoun Hur, Sang Kyum Kim, Hahyun Park, Hangun Kim   +8 more
wiley   +1 more source

Pigmented Basal Cell Carcinoma of the Umbilicus: Case Report

Journal of Dermatology and Dermatologic Surgery
Basal cell carcinoma (BCC) is the most frequent cutaneous malignancy in the light-skinned population worldwide. The large majority of BCCs arise around the head and neck, but they may occur at other sites, including the abdomen.
Prashansa Jaiswal, Akhilesh Shukla, Shiwangi Rana, Shilpi Shloka   +3 more
doaj   +1 more source

Dermoscopic Findings of Clonal Seborrheic Keratosis and Pigmented Basal Cell Carcinoma in the Skin of Color Patients - A Comparison. [PDF]

Indian Dermatol Online J, 2023
Jayasree P, Kaliyadan F, Ashique KT, Elizabeth M.   +3 more
europepmc   +1 more source

Cytology‐First Diagnostic Workflow for Melanoma of Unknown Primary With Molecular Profiling

Cytopathology, EarlyView.
Cytology‑first diagnostic workflow for melanoma of unknown primary. Fine‑needle aspiration of an enlarged lymph node enables rapid cytologic evaluation and immunocytochemical confirmation of melanocytic lineage (SOX10). This early cytologic diagnosis facilitates timely surgical excision and comprehensive genomic profiling, supporting integrated ...
Hong Yu, Mokhtar Abdelhammed, Xu Cao, Nisha S. Ramani   +3 more
wiley   +1 more source

Capillaroscopy in Pigmented Basal Cell Carcinoma Smaller than 3-mm Diameter: A Report of Four Lesions. [PDF]

Acta Derm Venereol, 2022
Saito S, Kuriyama Y, Uchiyama A, Yasuda M, Motegi SI.   +4 more
europepmc   +1 more source