Results 101 to 110 of about 4,236,773 (396)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

In-situ Combustion Pilot Basic Design and Laboratory Experiments

open access: yesGeoresursy, 2017
When it must be decided to develop a field with an enhanced oil recovery method, first it is needed to have a reservoir characterization model of high quality. Then the choice of the best suited method has to be carried out. For any method, a preliminary
C. Gadelle
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Application of integrating VC cross-connecting function with OTN system

open access: yesDianxin kexue, 2018
Due to the advantage of rigidity pipeline,SDH is irreplaceable in carrying high priority service circuit.However,it will withdraw because of equipment ageing.A solution of OTN system with VC cross-connecting function was proposed for the situation which ...
Heping LIN   +5 more
doaj  

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Badger culling pilots

open access: yesVeterinary Record, 2013
THE letter from Ranald Munro ( VR , June 8, 2013, vol 172, p 617), chair of the Independent Expert Panel (IEP) charged with overseeing the development of humaneness assessment protocols for the pilot badger culls and ensuring the robustness of data collection and analysis, and information Defra has so far released, both …
Mark, Jones   +11 more
openaire   +4 more sources

Optimizing Ship Pilotage with Intelligent Information Services: Integrating GIS-Based Big Data Positioning and Neural Network Approaches [PDF]

open access: yesJournal of Engineering, Project, and Production Management
The development of the shipping industry has put forward new requirements and challenges for its pilotage and services. To promote navigation development and ensure safe and efficient ship navigation, experiments have been conducted to combine ...
Yunye Ren
doaj   +1 more source

EVS: Head-up or Head Down? Evaluation of Crew Procedure and Human Factors for Enhanced Vision Systems [PDF]

open access: yes, 2009
Feasibility of an EVS head-down procedure is examined that may provide the same operational benefits under low visibility as the FAA rule on Enhanced Flight Visibility that requires the use of a head-up display (HUD).
Biella, M   +3 more
core  

“Getting Started”: A Pilot Introductory Narrative Writing Session for Interprofessional Faculty in Academic Health Sciences

open access: gold, 2022
Christy D Remein   +5 more
openalex   +2 more sources

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

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