Results 71 to 80 of about 4,236,773 (396)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Az Ovi-Sport Program pilot vizsgálata néhány debreceni óvodában

Különleges Bánásmód
Jelen tanulmány célja, hogy egyrészt bemutassa az Ovi-Sport Program kialakulását, lényegét és legfontosabb elemeit, másrészt egy empirikus alapú, pilot jellegű kérdőíves vizsgálat segítségével felmérje néhány debreceni óvoda óvodapedagógusának (n=52 ...
Éva Szabó , Dávid Rábai
doaj   +1 more source

Surgery versus conservative management of stable thoracolumbar fracture: the PRESTO feasibility RCT

Health Technology Assessment, 2021
Background: There is informal consensus that simple compression fractures of the body of the thoracolumbar vertebrae between the 10th thoracic vertebra and the second lumbar vertebra without neurological complications can be managed conservatively and ...
Elizabeth Cook, Arabella Scantlebury, Alison Booth, Emma Turner, Arun Ranganathan, Almas Khan, Sashin Ahuja, Peter May, Amar Rangan, Jenny Roche, Elizabeth Coleman, Catherine Hilton, Belén Corbacho, Catherine Hewitt, Joy Adamson, David Torgerson, Catriona McDaid   +16 more
doaj   +1 more source

Connections between the Academic Achievement, Vocational Selection, and Careers of Pilots

Social Sciences, 2023
Research demonstrates that a pilot should have specific skills and abilities. Therefore, professional aptitude tests developed by AGAI are used to select the best graduates for the pilot profession.
Vytautas Rimša, Aldona Radzevičienė, Mantvydas Latvėnas   +2 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Alarm system for insect migration using weather radars [PDF]

, 2008
The pilot system for forecasting insect migrations to next two days will be operated during May and June 2008. Forecasts are concentrating on two major pests; namely diamond-back moth and bird cherry aphid.
Koistinen, Jarmo, Leskinen, Matti, Markkula, Irmeli, Ojanen, Hannu, Ooperi, Sini, Pylkkö, Pirkko, Raiskio, Sakari, Tiilikkala, Kari   +7 more
core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Case Study: King County Rapid Re-Housing for Families Pilot [PDF]

, 2017
From 2013-15 in King County, Washington, the Rapid Re-Housing for Families pilot evaluated the effectiveness of enhancing rapid re-housing programming with employment navigators. This case study provides an overview of the pilot and its results.
Caitlin C. Schnur
core  

Dimethyl Fumarate Treatment Reduces the Amount but Not the Avidity of the Epstein–Barr Virus Capsid-Antigen-Specific Antibody Response in Multiple Sclerosis: A Pilot Study [PDF]

, 2023
Massimiliano Castellazzi, Caterina Ferri, Alice Piola, Samantha Permunian, Gaia Buscemi, Michele Laudisi, Eleonora Baldi, Maura Pugliatti   +7 more
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source