Results 161 to 170 of about 56,164 (284)

Personalized machine learning guided intervention for optimizing lifestyle behaviors in depression: a pilot study. [PDF]

NPP Digit Psychiatry Neurosci
Nan J, Purpura S, Jaiswal S, Afshar H, Maric V, Manchanda JK, Taylor CT, Ramanathan D, Mishra J.   +8 more
europepmc   +1 more source

Revisiting Target‐Aware de novo Molecular Generation with TarPass: Between Rational Design and Texas Sharpshooter

Advanced Science, EarlyView.
TarPass provides a rigorous benchmark for target‐aware de novo molecular generation by jointly evaluating protein‐ligand interactions, molecular plausibility, and drug‐likeness on 18 well‐studied targets. Results show that current models often fail to consistently surpass random baseline in target‐specific enrichment, while post hoc multi‐tier virtual ...
Rui Qin, Zijie Chen, Yurong Li, Meijing Fang, Longji Shen, Yilong Su, Odin Zhang, Qinghan Wang, Qun Su, Jike Wang, Tingjun Hou, Yu Kang   +11 more
wiley   +1 more source

A Transparent, Simple, Audit-Oriented Python-Based Binary Allocation Prototype for Clinical Research. [PDF]

Cureus
Malone KT.
europepmc   +1 more source

Data‐Driven Modeling of Composition–Processing–Microstructure Relations for Recycled Aluminum Cast Alloys

Advanced Science, EarlyView.
Interpretable machine learning reveals how composition and processing govern the formation and microstructural burden of Fe‐rich intermetallic compounds in recycled Al–Si–Fe–Mn alloys. By separating morphology selection from morphology‐conditioned burden partitioning, this framework shows that identical Fe contents can yield different intermetallic ...
Jaemin Wang, Waleed Mohammed, Dierk Raabe   +2 more
wiley   +1 more source

Piloting a Pragmatic Randomized Controlled Trial on the Effects of Integrated Psychosocial Care in Intensive Care Units (Phase B of the Integrated Psychosocial Care-Pilot Project): Protocol for a Feasibility Study. [PDF]

JMIR Res Protoc
Heytens H, Korger S, Nickel SF, Schindler W, Elgner M, Şahin KA, Krieg G, Schürmann K, Gehrig J, Brenner L, Binneböse M, Rose M, Gündel H, Junne F, Apfelbacher C.   +14 more
europepmc   +1 more source

GLS1 Orchestrates Exosome‐Mediated Tumor‐Endothelial Communication to Facilitate Angiogenesis

Advanced Science, EarlyView.
This study reveals a previously unappreciated, non‐metabolic function of GLS1 in the control of tumor angiogenesis via exosome‐mediated CAV1‐TNC signaling, indicating that therapeutic targeting of GLS1 may offer a dual benefit by simultaneously suppressing tumor metabolic activity and angiogenic processes in head and neck cancer. ABSTRACT Glutaminase 1
Jianqiang Yang, Zhenzhen Fu, Fanghui Chen, Soumya Vijaya Kumar, Fan Yang, Yaochao Zheng, Yunqi Li, Yao Yao, Nabil F. Saba, Yong Teng   +9 more
wiley   +1 more source

Enhancing patient engagement through an online educational module for gender-affirming mastectomy: A pilot study. [PDF]

JPRAS Open
Mehta NR, Mclaughlin M, Falade I, Song S, Yim C, Kim EA.   +5 more
europepmc   +1 more source

Design of Pilot Assignment for Large-Scale Distributed Antenna Systems

IEICE Transactions on Fundamentals of Electronics, Communications and Computer Sciences, 2016
Dongming Wang 0002, Heping Gu, Hao Wei 0003, Xiaoxia Duan, Chunguo Li, Xiaohu You 0001   +5 more
openaire   +1 more source

A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance

Advanced Science, EarlyView.
A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang, Tao Huang, Yiming Hao, Gui‐Feng Huang, Yi‐Lang Yan, Xin Fang, Ying Chen, Xiao‐Long Wei, Wai‐Lun Man, Wen‐Xiu Ni   +9 more
wiley   +1 more source

Mechanically Adaptive Polyimide Interfaces for Stable High‐Voltage NCM–Sulfide All‐Solid‐State Batteries

Advanced Science, EarlyView.
A mechanically adaptive polyimide interface dynamically stabilizes single‐crystal cathodes in sulfide all‐solid‐state batteries. By integrating robust chemical coordination with viscoelastic compliance, this smart coating suppresses parasitic reactions and accommodates cyclic volume expansion.
Jiatao Wu, Wenjin Li, Rui Wang, Peng Wang, Kaiyuan Deng, Chengshuai Chang, Chuan Xie, Lei Yao, Guangliang Gary Liu   +8 more
wiley   +1 more source