Results 71 to 80 of about 1,585,146 (310)

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Human Dimensions of Marine Fisheries: Using GIS to Illustrate Land-Sea Connections in the Northeast U.S. Herring, Clupea harengus, Fishery [PDF]

, 2005
Geographic Information Systems can help improve ocean literacy and inform our understanding of the human dimensions of marine resource use. This paper describes a pilot project where GIS is used to illustrate the connections between fish stocks and the ...
Da Silva, Patricia Pinto, Fulcher, Charles   +1 more
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

One-Year Pilot Study Results of Newborn Screening for Spinal Muscular Atrophy in the Republic of Croatia

International Journal of Neonatal Screening
Spinal muscular atrophy (SMA) is a neuromuscular and neurodegenerative disease caused by the homozygous deletion of SMN1 exon 7 in 95% of cases. The prognosis for SMA patients has improved with the development of disease-modifying therapies, all of which
Darija Šimić, Ana Šarić, Ana Škaričić, Ivan Lehman, Branka Bunoza, Ivana Rako, Ksenija Fumić   +6 more
doaj   +1 more source

Readiness and Success of Ubiquitous Learning in Indonesia: Perspectives from the Implementation of a Pilot Project

Information, 2019
The implementation of ubiquitous learning (u-learning) is a good opportunity to address the affordability, accessibility, and quality issues of the higher education sector that are present in many countries.
A’ang Subiyakto, Nur Aeni Hidayah, Gregoryo Gusti, Muhammad Ariful Hikami   +3 more
doaj   +1 more source

Development of a pilot data management infrastructure for biomedical researchers at University of Manchester – approach, findings, challenges and outlook of the MaDAM Project [PDF]

, 2012
Management and curation of digital data has been becoming ever more important in a higher education and research environment characterised by large and complex data, demand for more interdisciplinary and collaborative work, extended funder requirements ...
Beard, L. (Lorraine), Besson, Jon, Collins, S. (Simon), Finch, J. (June), Goff, Mhorag, Grahame, T. (Tom), McDerby, Mary, Poschen, Meik, Procter, Rob   +8 more
core   +3 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Preliminary results of the Pilot Project «Development of the Medical Rehabilitation System in the Russian Federation» in the city hospital № 26 (Saint Petersburg). Using «ICF reader» and the International Classification of Functioning for Setting Rehabili

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2016
This article focuses on the implementation of the pilot project «Development of the medical rehabilitation system in the Russian Federation» in the city hospital № 26 (Saint Petersburg).
A. A. Shmonin, M. N. Maltseva, V. V. Nikiforov, E. V. Melnikova, G. E. Ivanova, V. I. Dorofeev   +5 more
doaj   +1 more source