Results 61 to 70 of about 327,228 (301)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Potential Augmented Reality Application Areas for Pilot Education: An Exploratory Study

Education Sciences, 2020
The goal of carrying out this work was to identify potential application areas for augmented reality (AR) in pilot education by addressing gender preferences. Like the field of engineering, the aviation industry is dominated by men.
Harald Schaffernak, Birgit Moesl, Wolfgang Vorraber, Ioana Victoria Koglbauer   +3 more
doaj   +1 more source

The evaluation of the decision making processes employed by cadet pilots following a short aeronautical decision-making training program [PDF]

, 2006
Many aeronautical decision-making (ADM) mnemonic-based methods exist. However, there is no empirical research that suggests that they are actually effective in improving decision-making.
Harris, Don, Li, Wen-Chin
core  

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Evaluation of autism education trust training hubs programme. First data capture report : pilot of level 1 training [PDF]

The Autism Education Trust (AET) received a grant from the Department for Education (DfE) to deliver a programme of professional development and training to the school workforce (working with pupils aged 5 – 14) during 2011-2013.
Cullen, Mairi Ann, Cullen, Stephen Michael, Lindsay, Geoff, Charman, Tony   +3 more
core  

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source

Teknisen matkapäiväkirjajärjestelmän digitalisointi [PDF]

, 2019
Patria Pilot Training Oy:n jatkuvasti kasvava lentäjäkoulutustoiminta on luonut tarpeen toimintojen parantamiselle. Käytössä oleva paperinen lentokoneiden tekninen matkapäiväkirjajärjestelmä on todettu yhdeksi pullonkaulaksi tehokkaalle toiminnalle ...
Silander, Rasmus
core  

Making in-class skills training more effective: the scope for interactive videos to complement the delivery of practical pedestrian training

, 2015
Skills and awareness of young pedestrians can be improved with on-street practical pedestrian training, often delivered in schools in the United Kingdom by local authorities with the intention of improving road safety. This training is often supplemented
Tom Cherrett, James Hammond, Hammond, James, Waterson, Ben, Cherrett, Tom, Ben Waterson   +5 more
core   +1 more source

Do ACE inhibitors improve the response to exercise training in functionally impaired older adults? A randomized controlled trial [PDF]

, 2014
<br>Background: Loss of muscle mass and strength with ageing is a major cause for falls, disability, and morbidity in older people. Previous studies have found that angiotensin-converting enzyme inhibitors (ACEi) may improve physical function in ...
Sumukadas, Deepa, Cvoro, Vera, McMurdo, Marion, Lloyd, Suzanne M., Band, Margaret, Miller, Suzanne, Witham, Miles, Struthers, Allan, McConnachie, Alex   +8 more
core   +1 more source