Results 91 to 100 of about 4,197,402 (332)

Use of the tilt cue in a simulated heading tracking task [PDF]

open access: yes, 1978
The task was performed with subjects using visual-only cues and combined visual and roll-axis motion cues. Half of the experimental trials were conducted with the simulator rotating about the horizontal axis; to suppress the tilt cue, the remaining ...
Junker, A. M., Levison, W. H.
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

A Pilot Study Investigating the Feasibility and Acceptability of a Parent-Only Behavioral Weight-Loss Treatment for Children with Autism Spectrum Disorder. [PDF]

open access: yes, 2019
Evidence-based weight-loss treatments for children with autism spectrum disorder (ASD) are lacking. Therefore, a parent-based weight-loss treatment for children with ASD (PBT-ASD) was developed.
Boutelle, Kerri N   +2 more
core   +1 more source

Morita Therapy for depression (Morita Trial): a pilot randomised controlled trial [PDF]

open access: yesBMJ Open, 2018
ObjectiveTo address uncertainties prior to conducting a fully powered randomised controlled trial of Morita Therapy plus treatment as usual (TAU) versus TAU alone, or to determine that such a trial is not appropriate and/or feasible.DesignPilot parallel group randomised controlled feasibility trial.Setting and participantsParticipants aged ≥18 years ...
Holly Victoria Rose Sugg   +2 more
openaire   +3 more sources

Methods and processes for development of a CONSORT extension for reporting pilot randomized controlled trials

open access: yesPilot and Feasibility Studies, 2016
BackgroundFeasibility and pilot studies are essential components of planning or preparing for a larger randomized controlled trial (RCT). They are intended to provide useful information about the feasibility of the main RCT—with the goal of reducing ...
L. Thabane   +6 more
semanticscholar   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Impact of the coating process on the molecular structure of starch-based barrier coatings [PDF]

open access: yes, 2014
Molecular analysis of starch structure can be used to explain and predict changes in physical properties, such as water vapor and oxygen barrier properties in packaging materials.
Altskär   +23 more
core   +1 more source

Improving the efficiency of trials using innovative pilot designs: the next phase in the conduct and reporting of pilot and feasibility studies

open access: yesPilot and Feasibility Studies, 2017
With continuously increasing costs of conducting trials, use of innovative approaches—such as pragmatic trials, registry-based randomised trials, adaptive trials, personalised medicine trials, platform trials, and basket trials—to the design and conduct ...
L. Thabane, G. Lancaster
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

A feasibility study for the provision of electronic healthcare tools and services in areas of Greece, Cyprus and Italy [PDF]

open access: yes, 2011
Background: Through this paper, we present the initial steps for the creation of an integrated platform for the provision of a series of eHealth tools and services to both citizens and travelers in isolated areas of thesoutheast Mediterranean, and on ...
Androulidakis, Aggelos   +10 more
core   +7 more sources

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