Results 181 to 190 of about 37,543 (291)

The Alberta Telestewardship Network: Building a platform to enable capacity building in antimicrobial stewardship-results of an initial pilot study. [PDF]

J Assoc Med Microbiol Infect Dis Can, 2023
Jelinski D, Julien D, Cook S, Harris S, Logan T, Sabuda D, Dersch-Mills D, Wong C, Webster S, Constantinescu C, Hoang H, Conly J.   +11 more
europepmc   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

Advanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher, Victoria Lorant, Valerie Rochon, Abigail Carter, Cameron Stotts, My‐Anh Nguyen, Thomas Laval, Christina Emerton, Nathan Joyce, Nysa Vinayak, Marlena Scaffidi, David Cook, Katey J. Rayner, Rebecca C. Auer, Scott M. Gordon, Mireille I. Ouimet   +15 more
wiley   +1 more source

Identification and Prioritization of Canadian Society of Nephrology Clinical Practice Guideline Topics With Multidisciplinary Stakeholders and People Living With Kidney Disease: A Clinical Research Protocol. [PDF]

Can J Kidney Health Dis, 2023
Baragar BH, Schorr M, Verdin N, Woodlock T, Clark DA, Hundemer GL, Mathew A, Mustafa RA, Ryz KS, Harrison TG.   +9 more
europepmc   +1 more source

Analyse des quartiers pilotes sQUAD : rapport complet [PDF]

, 2015
Boni, A., Boulanger, E., Cemesova, S., Desthieux, G., Esteve-Floch, L., Guiavarch, A., Guillot, V., Hmidan-Kocherhans, A., Horber-Papazian, K., Jacot-Descombes, C., Kuchler, F., Michel, D., Villard, J.   +12 more
core  

Mesoscale Recovery of Microglial and Neuronal Dynamics After Craniotomy Across Wide Cortex in Transgenic Mice

Advanced Science, EarlyView.
This study employs longitudinal fluorescence imaging in transgenic mice to map post‐craniotomy cortical recovery. We identify distinct neuroimmune recovery phases: microglial structural inflammation peaks at ∼10 days, neuronal structural intensity peaks at ∼14 days and correlates with microglial activity, and functional network modularity is most ...
Guihua Xiao, Zhilei Wang, Pengchang Zheng, Jingyu Xie, Yangzhen Wang, Yun Chen, Zilin Wang, Ao Li, Minghuan Wang, Quanbo Ji, Can Gao, Di Yao, Lingbo Li, Jiangbei Cao   +13 more
wiley   +1 more source

Rheumatic Heart Disease: Global Failure in Tackling a Common Killer. [PDF]

CJC Open
Manuel V, Mocumbi AO, Zühlke L.
europepmc   +1 more source

Systematic Evaluation of a Provincial Initiative to Improve Transition to Home Dialysis Therapies. [PDF]

Can J Kidney Health Dis, 2020
Wang A, Turnbull L, Williams J, Thomas S, Saunders S, Levin A, Djurdjev O, Copland M, Singh S, Hemmett J.   +9 more
europepmc   +1 more source

A Wearable Brain–Computer Interface for Mitigating Car Sickness via Attention Shifting

Advanced Science, EarlyView.
Car sickness poses a major challenge in vehicular travel, yet effective nonpharmacological solutions are scarce. We developed a wearable, closed‐loop mindfulness BCI that uses real‐time EEG‐based neurofeedback to shift attention away from motion‐induced discomfort. Validated in real‐car experiments involving >100$>100$ susceptible individuals, over 83%
Jiawei Zhu, Xiaoyu Bao, Qiyun Huang, Tao Wang, Li Huang, Haiyun Huang, Junbiao Zhu, Jun Qu, Kendi Li, Di Chen, Ya Jiang, Kailin Xu, Zijian Wang, Wei Wu, Yuanqing Li   +14 more
wiley   +1 more source

La cimentación de las torres de la Plaza de España de Sevilla: regionalismo e innovación tecnológica en los años 1920 [PDF]

, 2009
Díaz del Río Martínez, Luis, Jaramillo-Morilla, Antonio, Mascort-Albea, Emilio J., Povedano Molina, José Enrique, Ruiz-Jaramillo, Jonathan   +4 more
core