Results 31 to 40 of about 37,543 (291)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Energy Production Based on the Chain’s Service Area Size in Biomethane Recovery
EnergiesThis article studies the chain’s service area size in biomethane recovery from municipal organic waste, with a model created to study the energy generated, which may be applied to determine the optimal allocation of waste and location of the digester ...
Rosario Corbo, Mathias Glaus
doaj +1 more source
Informes de la Construccion, 1962 Un primer proyecto estaba formado por catorce tramos de 20 metros de luz sobre pilas cimentadas a 4 metros de profundidad en la parte cubierta solamente por las grandes avenidas, y con cimentaciones sobre pilotes de 10 metros en los tres tramos cubiertos
Eduardo Torroja
doaj +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Energies, 2018 Diverse factors may have an impact in carbon dioxide (CO2) emissions; thus, three main contributors, energy consumption, gross domestic product (GDP) and an exergy indicator are examined in this work. This study explores the relationship between economic
Raúl Arango-Miranda +4 more
doaj +1 more source
Disseny d’una màquina dispensadora de pilotes de golf [PDF]
, 2008 El projecte consisteix en el disseny d’una màquina dispensadora de pilotes de golf. La demanda d’aquest tipus de màquines és petita i per tant, l’oferta que les empreses relacionades amb l’àmbit del golf han generat també és petita.
Muñoz Carceller, Virgili
core
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Revista Técnica de la Facultad de Ingeniería, 2014 En la práctica normal de ingeniería de cimentaciones se calcula la capacidad de carga del pilote sin tener en cuenta que el proceso constructivo puede afectar el componente geométrico de la ecuación de la capacidad portante.
Cristhian Mendoza Cristhian Mendoza +3 more
doaj
Natures Sciences Sociétés, 2018 La principale innovation du mécanisme de réduction des émissions issues de la déforestation et de la dégradation des forêts (REDD+) est de proposer un mécanisme de conservation des forêts par l’incitation économique basé sur les résultats.
Brimont Laura, Leroy Maya
doaj +1 more source