Results 41 to 50 of about 37,543 (291)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Blind Pilot Decontamination [PDF]

open access: yesIEEE Journal of Selected Topics in Signal Processing, 2014
A subspace projection to improve channel estimation in massive multi-antenna systems is proposed and analyzed. Together with power-controlled hand-off, it can mitigate the pilot contamination problem without the need for coordination among cells. The proposed method is blind in the sense that it does not require pilot data to find the appropriate ...
Müller, Ralf R.   +2 more
openaire   +4 more sources

Définir un package pour inciter les pilotes de jet privé à atterrir à l’aéroport de Sion [PDF]

open access: yes, 2018
Ce travail de bachelor met en lumière l’expérience vécue par les pilotes de jet privé lors de leurs atterrissages au coeur des alpes. Toutes les étapes de leurs quotidens ont pu être dévoilées grâce à l’usage aux outils et techniques modernes du ...
Fragnière, Emmanuel, Malicho, Natacha
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Hojas de cálculo para el análisis de losas combinadas con pilotes

open access: yesRevista Ingeniería de Construcción, 2013
En el diseño de cimentaciones en balsas combinadas con pilotes, se determina un gran número de incógnitas de forma tal que se obtenga una cimentación racional y que a su vez cumpla con los requerimientos de proyecto.
Luis Ibañez, Cunha Renato
doaj   +1 more source

Cargas de hundimiento por punta de pilotes en roca: estudio comparativo [PDF]

open access: yes, 2010
En el presente documento se realiza un estudio comparativo de las formulaciones definidas, tanto por la literatura técnica como por las diferentes normativas nacionales e internacionales más relevantes, para la determinación de la carga de hundimiento ...
Juarez Millan, Francisco   +2 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Optimización de una cimentación pilotada y de la superestructura de un centro comercial mediante simulación de la interacción terreno-estructura en suelos licuefactables con un caso de sismo dimensionante : análisis comparativo de los resultados con y sin interacción terreno estructura [PDF]

open access: yes, 2015
Congreso celebrado en la Escuela de Arquitectura de la Universidad de Sevilla desde el 24 hasta el 26 de junio de 2015.Soil-structure interaction techniques have been widely written about and largely used in the Energy domain, even if they are still not ...
Cantó, José Vicente   +2 more
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks   +10 more
wiley   +1 more source

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