Results 71 to 80 of about 221,719 (219)

Food effect risk assessment in preformulation stage using material sparing µFLUX methodology

ADMET and DMPK, 2022
The intake of food and meal type can strongly impact the bioavailability of orally administered drugs and can consequently impact drug efficacy and safety.
Corinne Jankovsky, Oksana Tsinman, Naveen Thakral   +2 more
doaj   +1 more source

In silico, in vitro and ex vivo characterization of cystic fibrosis transmembrane conductance regulator pathogenic variants localized in the fourth intracellular loop and their rescue by modulators

British Journal of Pharmacology, Volume 182, Issue 24, Page 6063-6080, December 2025.
Background and Purpose Cystic fibrosis (CF) is due to loss‐of‐function variants of the CF transmembrane conductance regulator (CFTR) channel. The most effective treatment for people with CF carrying the F508del mutation is the triple combination of elexacaftor–tezacaftor–ivacaftor (ETI).
Emanuela Pesce, Valeria Tomati, Valeria Capurro, Mariateresa Lena, Cristina Pastorino, Miro Astore, Serdar Kuyucak, Benoit Chevalier, Elvira Sondo, Federico Cresta, Alice Dighero, Vito Terlizzi, Cristina Fevola, Stefano Costa, Maria Cristina Lucanto, Valeria Daccò, Laura Claut, Francesca Ficili, Benedetta Fabrizzi, Renata Bocciardi, Federico Zara, Carlo Castellani, Luis J. V. Galietta, Shafagh A. Waters, Alexandre Hinzpeter, Nicoletta Pedemonte   +25 more
wiley   +1 more source

Pion generalized parton distributions and light-front wave functions in the Nambu–Jona-Lasinio model

Nuclear Physics B, 2021
Pion generalized parton distributions and light-front wave functions are investigated in the framework of Nambu–Jona-Lasinio model. The properties of pion generalized parton distributions and light-front wave functions are examined separately. Proceeding
Jin-Li Zhang, Meng-Yun Lai, Hong-Shi Zong, Jia-Lun Ping   +3 more
doaj   +1 more source

Determination of the pion distribution amplitude

, 2013
Right now, we have not enough knowledge to determine the hadron distribution amplitudes (DAs) which are universal physical quantities in the high energy processes involving hadron for applying pQCD to exclusive processes.
Huang, Tao, Wu, Xing-Gang, Zhong, Tao
core   +1 more source

Bioactivity and physicochemical characterization of Centella asiatica and Marigold extract serums: Antioxidant, anti‐inflammatory, anti‐tyrosinase and skin barrier function insights

International Journal of Cosmetic Science, Volume 47, Issue 6, Page 1070-1084, December 2025.
Evaluation of Centella asiatica extract and Marigold extract serums, optimizing their concentrations for antioxidant, anti‐inflammatory, antibacterial, and skin barrier‐enhancing effects. It uniquely combines bioactivity, stability, and permeability assessments, revealing Centella asiatica extract's superior regenerative potential and Marigold extract ...
Rizos Evangelos Bikiaris, Magdalena Paczkowska‐Walendowska, Ioanna Koumentakou, Argyri Niti, Judyta Cielecka‐Piontek, George Z. Kyzas   +5 more
wiley   +1 more source

On the impact of mass difference between the pions (π±-π0) and the nucleons (n-p) on the charge independence breaking of nuclear forces

Ядерна фізика та енергетика, 2017
Charge dependence of the pion-nucleon coupling constants and the 1S0-state low-energy nucleon-nucleon scattering parameters are studied on the basis of the Yukawa meson theory.
V. A. Babenko, N. M. Petrov
doaj  

Cosmic Ray Counting Variability From Water‐Cherenkov Detectors as a Proxy of Stratospheric Conditions in Antarctica

Earth and Space Science, Volume 12, Issue 11, November 2025.
Abstract This work examines atmospheric effects on cosmic ray counts observed by a Water‐Cherenkov detector at the Argentine Antarctic Marambio Station. We analyze the influence of ground‐level barometric pressure and geopotential height at various pressure levels on daily particle rates, finding the strongest association at 100 hPa, linked to ...
N. A. Santos, N. Gómez, S. Dasso, A. M. Gulisano, L. Rubinstein, M. Pereira, O. Areso, for the LAGO Collaboration   +7 more
wiley   +1 more source

Evaluation of the two lightest quark masses

Ядерна фізика та енергетика, 2017
Simple relations between the masses of the two lightest up and down quarks were obtained on the basis of the simple physically based model compatible with the present-day theory of strong interactions, i.e. with quantum chromodynamics.
V. A. Babenko, N. M. Petrov
doaj  

Pion transverse-momentum spectrum and elliptic anisotropy of partially coherent source

Physics Letters B, 2018
In this letter, we study the pion momentum distribution of a coherent source and investigate the influences of coherent emission on the pion transverse-momentum (pT) spectrum and elliptic anisotropy.
Peng Ru, Ghulam Bary, Wei-Ning Zhang
doaj   +1 more source

Pion-Nucleon Scattering and Pion-Pion Interaction [PDF]

Progress of Theoretical Physics, 1962
Applying Cini-Fubini approximation to the Mandelstam representation for pion-nucleon scattering amplitude, we treat explicitly the effect of pion-pion interaction to be added to the dispersion relation given by Chew, Goldberger, Low and Nambu. On account of scanty information on the contribution to tl:e dispersion .integral from high-mass states, we ...
openaire   +1 more source