Results 31 to 40 of about 3,927,919 (281)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Secondary vortex-based analysis of flow characteristics and pressure drop in helically coiled pipe

open access: yesAdvances in Mechanical Engineering, 2017
This article presents an investigation for the secondary flow characteristics and associated pressure loss in fluid flow through helically coiled pipe.
Lingdi Tang   +3 more
doaj   +1 more source

Thermal Analysis in Pipe Flow: Influence of Variable Viscosity on Entropy Generation

open access: yesEntropy, 2004
: Flow through pipes and heating situations find wide applications in industry. Depending on the fluid properties, temperature field in the pipe changes. This in turn results in thermodynamic irreversibility in the flow system.
Bekir Sami Yilbas   +1 more
doaj   +1 more source

Flow Topology in the Confluence of an Open Channel with Lateral Drainage Pipe

open access: yesHydrology, 2020
The purpose of this paper is to develop design guidelines for flood control channel height in the vicinity of the confluence of a submerged drainage pipe and a flood control channel.
Mohammad Nazari-Sharabian   +2 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Research on Mixing Law of Liquid Fertilizer Injected into Irrigation Pipe

open access: yesHorticulturae, 2022
The time and position that fertilizer takes to uniformly mix with water in an irrigation system significantly affects the development of a fertilization strategy.
Zhiyang Zhang   +3 more
doaj   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

open access: yesFEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa   +4 more
wiley   +1 more source

Efficiency of osmotic pipe flows [PDF]

open access: yesPhysical Review E, 2013
We present experiments and theory for flows of sugar or salt solutions in cylindrical tubes with semipermeable walls (hollow fiber membranes) immersed in water, quantifying the strength of the osmotic driving force in relation to the dimensionless parameters that specify the system.
Haaning, Louise Sejling   +4 more
openaire   +3 more sources

Two-phase flow patterns in turbulent flow through a dose diffusion pipe [PDF]

open access: yes, 2005
A numerical investigation is carried out for turbulent particle-laden flow through a dose diffusion pipe for a model reactor system. A Lagrangian Stochastic Monte-Carlo particle-tracking approach and the averaged Reynolds equations with a k-e turbulence ...
Tang, H   +5 more
core   +1 more source

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