A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee +8 more
wiley +1 more source
PeakPrime: a peak-guided primer design pipeline for target enrichment in 3'-end RNA-seq. [PDF]
Poma-Soto F +4 more
europepmc +1 more source
Metal‐free carbon catalysts enable the sustainable synthesis of hydrogen peroxide via two‐electron oxygen reduction; however, active site complexity continues to hinder reliable interpretation. This review critiques correlation‐based approaches and highlights the importance of orthogonal experimental designs, standardized catalyst passports ...
Dayu Zhu +3 more
wiley +1 more source
A Reproducible Python-Based Computational Pipeline for Real-Time Ingestion, Advanced Analysis, and Dynamic Reporting of Public Health Data: A Systems Validation Study. [PDF]
Krishnapur PK, Cm C, B A, M A.
europepmc +1 more source
Light‐Induced Entropy for Secure Vision
This work realized a ternary true random number generator by exploiting stochastic traps emerging within multiple junction interfaces, and quantitatively validated the generation of high‐quality random numbers. Furthermore, it successfully demonstrated diverse applications, including AI‐resilient image security, thereby providing a valuable guide for ...
Juhyung Seo +9 more
wiley +1 more source
Lightweight Semantic-Aware Route Planning on Edge Hardware for Indoor Mobile Robots: Monocular Camera-2D LiDAR Fusion with Penalty-Weighted Nav2 Route Server Replanning. [PDF]
Abaza BF, Staicu AA, Doicin CV.
europepmc +1 more source
Bottom‐Up Programming of Cell States in Cancer Organoids with Defined Synthetic Adhesion Cues
A bottom‐up biomaterial platform is developed to program transcriptomic states in pancreatic cancer organoids by tuning adhesion cues within synthetic matrices. By combining a Design of Experiments framework with multiobjective optimization, matrix compositions are identified that enrich specific cellular programs like EMT.
Ali Nadernezhad +6 more
wiley +1 more source
A clinically informed automated evaluation pipeline for medical image segmentation based on Medical Similarity Index. [PDF]
Fazekas S +4 more
europepmc +1 more source
Metamaterial Antennas Enhance MRI of the Eye and Occipital Brain
A radiofrequency antenna platform comprising planar and bend configurations is developed, incorporating structurally integrated epsilon‐negative metamaterial unit cells to enhance MRI. These antennas enable high‐resolution in vivo human MRI of the eye, orbit, and occipital brain. Comprehensive validation, including simulations, phantom experiments, SAR,
Nandita Saha +14 more
wiley +1 more source

