Generative tissue modeling for customized biomechanical analysis: a data-driven synthesis framework of simulation-ready 3D shapes. [PDF]
Ma J +9 more
europepmc +1 more source
A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen +13 more
wiley +1 more source
Scaling medical device regulatory science using large language models. [PDF]
Li H +6 more
europepmc +1 more source
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
EMoMiS: A pipeline for epitope-based molecular mimicry search in protein structures with potential applications to SARS-CoV-2. [PDF]
Stebliankin V +14 more
europepmc +1 more source
A semi-automated pipeline integrating ImageJ/Fiji and StarDist for the reproducible quantification of cellular and optical density metrics in immunofluorescence images of brain tissue. [PDF]
Marques SI +4 more
europepmc +1 more source
Hierarchical YOLO-SAM: A Scalable Pipeline for Automated Segmentation and Morphometric Tracking of Coral Recruits in Time-Series Microscopy. [PDF]
Zhao RS, Chen C, Van Horn M, Fogarty ND.
europepmc +1 more source
Intent-driven LLM ensemble planning for flexible multi-robot manipulation. [PDF]
Erdogan C +4 more
europepmc +1 more source
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