Results 31 to 40 of about 12,949 (265)

Ductile Fracture Prediction of X80 Pipeline Steel Using Void Growth Model

Metals, 2022
In this study, the Void Growth Model (VGM) is employed to predict the ductile fracture of X80 pipeline steel. The X80 pipeline tends to be applied in challenging scenarios, such as extremely deep water and long-distance pipelines, which might cause a ...
Chunjian Feng, Zengli Peng, Xin Li, Shiliu Bao, Ximin Jiang   +4 more
doaj   +1 more source

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris, Priya B. Shetty, Olga A. Taylor, Elizabeth G. Atkinson, Melissa A. Richard, M. Monica Gramatges, Mark Zobeck, Sandi Pruitt, Amy Hughes, M. Brooke Bernhardt, Ashley Chavana, Van Huynh, Kathleen Ludwig, Laura Klesse, Kenneth Heym, Timothy Griffin, Rodrigo Erana, Juan Carlos Bernini, Han Chen, Bing Yu, Philip J. Lupo, Karen R. Rabin, Michael E. Scheurer, Austin L. Brown, The REDIAL Consortium   +24 more
wiley   +1 more source

Microstructure and Strengthening/Toughening Mechanisms of Heavy Gauge Pipeline Steel Processed by Ultrafast Cooling

Metals, 2020
Heavy gauge pipeline steels experience a low qualification in drop-weight-tear test properties because of the low cooling capability of conventional thermomechanical controlled processing.
Xue-qiang Wang, Guo Yuan, Jin-hua Zhao, Guo-dong Wang   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Corrosion behavior of X100 pipeline steel and its heat-affected zones in simulated Korla soil solution under alternating current interference

工程科学学报, 2020
In recent years, many accidents caused by alternating current (AC) corrosion have been reported. AC corrosion has become a serious potential damage to buried steel pipelines.
Yong YANG, Xin-hua WANG, Ying-chun CHEN, Kai-ling WEI   +3 more
doaj   +1 more source

Research progress and prospect of key technologies for high-strain line pipe steel and pipes

Natural Gas Industry B, 2021
The development and supporting technologies of high-strain line pipe steel and pipes used for oil and gas pipeline projects in special geological environments (such as earthquake zone, landslide zone, mine goaf and subsidence zone) is one of the ...
Yaorong Feng, Lingkang Ji, Hongyuan Chen, Jinxing Jiang, Xu Wang, Yi Ren, Duihong Zhang, Hui Niu, Mingzhuo Bai, Shaopo Li   +9 more
doaj   +1 more source

DIAGNOSTICS AND RENOVATION METHODS FOR STEEL PIPELINES

International Journal for Computational Civil and Structural Engineering
The article explores the analytical challenges and potential applications of diagnostic equipment and tools for cost-effective restoration of aging pressure pipeline systems at minimum costs for water transportation. The study focuses on a section of a water supply network made of steel pipes that requires repair and restoration due to corrosion damage
Dmitrii Vladimirovich Podolian, Vladimir Aleksandrovich Orlov, Artemiy Vasilevich Gorelov   +2 more
openaire   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source