Results 31 to 40 of about 12,885 (266)
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
You-qi chuyun, 2020 Failure of girth welds in high-grade steel pipelines is common. With the surge in mileages of high-grade steel pipeline, the failure of girth weld in high-grade steel pipelines has drawn an increasing attention from domestic and foreign pipeline ...
Zhenyong ZHANG
doaj +1 more source
Ductile Fracture Prediction of X80 Pipeline Steel Using Void Growth Model
Metals, 2022 In this study, the Void Growth Model (VGM) is employed to predict the ductile fracture of X80 pipeline steel. The X80 pipeline tends to be applied in challenging scenarios, such as extremely deep water and long-distance pipelines, which might cause a ...
Chunjian Feng +4 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
Metals, 2020 Heavy gauge pipeline steels experience a low qualification in drop-weight-tear test properties because of the low cooling capability of conventional thermomechanical controlled processing.
Xue-qiang Wang +3 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
Evaluation on pressure bearing capacity of X70 pipeline with pure dent defect
You-qi chuyun, 2020 In order to evaluate the ultimate pressure bearing capacity of high-grade steel pipeline with pure dent defect, finite element analysis was performed for the deformation of steel pipeline during the formation of dent and the hydraulic test.
Peng SONG +5 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng +4 more
wiley +1 more source
Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach +23 more
wiley +1 more source
Research progress and prospect of key technologies for high-strain line pipe steel and pipes
Natural Gas Industry B, 2021 The development and supporting technologies of high-strain line pipe steel and pipes used for oil and gas pipeline projects in special geological environments (such as earthquake zone, landslide zone, mine goaf and subsidence zone) is one of the ...
Yaorong Feng +9 more
doaj +1 more source