Results 161 to 170 of about 182,979 (366)

Piping Cracks in JPDR, (II) [PDF]

open access: bronze, 1978
Yoshiaki Futamura   +2 more
openalex   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

open access: yesAdvanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He   +17 more
wiley   +1 more source

Experimental Assessment of Stress-Strain Response in Filament-Wound GFRP Pipes Under Internal Pressure Loading. [PDF]

open access: yesMaterials (Basel)
Ilincă CN   +8 more
europepmc   +1 more source

A technique for making clean holes in metallic piping and components [PDF]

open access: yes
Testing was conducted to develop a technique of providing clean holes in process piping or in a metal surface accessible from one side only without disassembling the system. The method was performed on sample pieces of piping and worked successfully with
Hecker, T. P.
core   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

open access: yesAdvanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore   +20 more
wiley   +1 more source

TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network

open access: yesAdvanced Science, EarlyView.
A retinoic acid receptor agonist, TTNPB, drives the efficient generation of advanced neural stem cells (ANSCs) from human pluripotent stem cells. TTNPB‐centered chromatin remodeling and metabolic reprogramming, promote neuroectoderm commitment. The resulting cells show robust neural potential and functional efficacy in a rat depression model.
Ruilin Du   +17 more
wiley   +1 more source

Unveil Fundamental Graph Properties for Neural Architecture Search

open access: yesAdvanced Science, EarlyView.
This paper proposes NASGraph, a graph‐based framework that represents neural architectures as graphs whose structural properties determine performance. By revealing structure–performance relationships, NASGraph enables efficient neural architecture search with significantly reduced computation.
Zhenhan Huang   +4 more
wiley   +1 more source

Modular Design of Vacuum Systems for Lyophilization. [PDF]

open access: yesInd Eng Chem Res
Stratta L   +7 more
europepmc   +1 more source

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