Results 31 to 40 of about 41,888 (252)
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Cuadernos de Investigación Geográfica, 2013 Los procesos de piping o sufosión se han observado en paisajes naturales y antrópicos, en diferentes litologías y climas, y bajo diferentes usos del suelo y cubiertas vegetales.
E. Nadal-Romero +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
AVALIAÇÃO DA SUSCEPTIBILIDADE DE SOLOS GNAISSICOS À EROSÃO SUBSUPERFICIAL / Evaluation of piping erosion susceptibility in gnaissic soils [PDF]
Sociedade & Natureza, 2007 The basement rock areas of the Maracujá hydrographic basin show great incidence of hugegullies. This work aims to investigate the influence of the underground erosive processes inthe evolution of these features and to understand how the mineralogical and
Frederico Garcia Sobreira +2 more
doaj
Arthritis Care &Research, EarlyView.Objective This study aimed to investigate hand function trajectories over five years in primary hand osteoarthritis (OA). Additionally, determinants of baseline and longitudinal hand function were assessed. Methods A total of 538 patients with both baseline and five‐year study visits were analyzed.
Annemiek V. E. M. Olde Meule +4 more
wiley +1 more source
Mechanical Engineering JournalThe importance of seismic probabilistic risk assessment has drawn considerable attention for improving the seismic safety of nuclear facilities against earthquakes that exceed the design input ground motion.
Yukihiko OKUDA +3 more
doaj +1 more source
Mechanical Engineering Journal, 2018 This paper describes the J-integral evaluation methods for the case of multiple circumferential cracks in a cylinder subjected to bending moments. J-integral is one of the parameters of fracture mechanics used in the fracture assessment of materials that
Hideo MACHIDA +3 more
doaj +1 more source
Advanced Engineering Materials, EarlyView.A numerical–experimental framework is developed for characterizing multi‐matrix fiber‐reinforced polymers (MM‐FRPs) combining epoxy and polyurethane matrices. Harmonic bending tests are integrated with finite element model updating (FEMU) to simultaneously identify elastic and viscoelastic material parameters.
Rodrigo M. Dartora +4 more
wiley +1 more source
Experimental Study of Soil Texture and Cross River Structures on Depth of Undercutting Hole Induced by Seepage Erosion in River Banks [PDF]
علوم و مهندسی آبیاری, 2012 Despite of many researches on bank erosion mechanism, there exists an incomplete understanding of one of the basic mechanisms governing sediment loading to streams which is namely erosion by concentrated lateral, subsurface flow which causes river bank ...
Hediyeh Salamatravandi +3 more
doaj
Advanced Engineering Materials, EarlyView.This article presents the design, modeling, and characterization of air‐pressure–actuated programmable vibroacoustic metamaterials (PVAMM). The study focuses on leveraging air pressure to dynamically tune resonance frequencies for effective noise attenuation.
William Kaal +2 more
wiley +1 more source