Results 31 to 40 of about 8,311 (268)

Experimental study on the change law of internal erosion and seepage characteristics of inverse grading sand accumulation

地质科技通报, 2023
Inverse grading deposits are commonly found in circulation and accumulation areas of high-speed and long-distance landslides. Due to its special structure of large particle size at the top and small at the bottom and strong permeability, the accumulation
Yixiang Song, Jinghua Guan, Yanqi Li, Da Huang   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Influence of piping processes on the relief evolution. Bardenas Reales (Navarra, Spain)

Cuadernos de Investigación Geográfica, 2013
Piping processes are controlled by many interacting factors, such as dispersion index and sodium content, SAR and ESP, together with other important factors as cracking density, slope degree and climate.
G. Desir, C. Marín
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Una nueva herramienta para evaluar la susceptibilidad de los suelos a los procesos de sufosión o piping : el pinhole test

Cuadernos de Investigación Geográfica, 2013
Los procesos de piping o sufosión se han observado en paisajes naturales y antrópicos, en diferentes litologías y climas, y bajo diferentes usos del suelo y cubiertas vegetales.
E. Nadal-Romero, E. Verachtert, R. Maes, J. Poesen   +3 more
doaj   +1 more source

Integrating Patient‐Reported Quality Measures in Systemic Lupus Erythematosus: Development of the American College of Rheumatology Implementation Guide

Arthritis Care &Research, EarlyView.
Objective To support high‐quality, patient‐centered care for systemic lupus erythematosus (SLE), the American College of Rheumatology (ACR) developed evidence‐based measures incorporating clinical and patient‐reported outcome measures (PROMs). Using the Consolidated Framework for Implementation Research (CFIR), we conducted semistructured interviews ...
Catherine Nasrallah, Cherish Wilson, Christine Hariz, Christie M. Bartels, Shanthini Kasturi, Wambui Machua, Amy Bennett, Kate Chiseri, Allison Plitman, Starla Hairston Blanks, April Jorge, Patti Katz, Jinoos Yazdany, Shivani Garg   +13 more
wiley   +1 more source

Investigation on damage evaluation index with ductility factor based on simulation analysis for loading test of piping support structure

Mechanical Engineering Journal
The importance of seismic probabilistic risk assessment has drawn considerable attention for improving the seismic safety of nuclear facilities against earthquakes that exceed the design input ground motion.
Yukihiko OKUDA, Kiyotaka TAKITO, Akemi NISHIDA, Yinsheng LI   +3 more
doaj   +1 more source

AVALIAÇÃO DA SUSCEPTIBILIDADE DE SOLOS GNAISSICOS À EROSÃO SUBSUPERFICIAL / Evaluation of piping erosion susceptibility in gnaissic soils [PDF]

Sociedade & Natureza, 2007
The basement rock areas of the Maracujá hydrographic basin show great incidence of hugegullies. This work aims to investigate the influence of the underground erosive processes inthe evolution of these features and to understand how the mineralogical and
Frederico Garcia Sobreira, Luis Almeida Prado Bacellar, Fernando Morais   +2 more
doaj  

Biopsychosocial Determinants of Hand Function and Its Trajectories Over Five Years in Patients With Hand Osteoarthritis

Arthritis Care &Research, EarlyView.
Objective This study aimed to investigate hand function trajectories over five years in primary hand osteoarthritis (OA). Additionally, determinants of baseline and longitudinal hand function were assessed. Methods A total of 538 patients with both baseline and five‐year study visits were analyzed.
Annemiek V. E. M. Olde Meule, Coen van der Meulen, Jos Runhaar, Frits R. Rosendaal, Margreet Kloppenburg   +4 more
wiley   +1 more source