Results 81 to 90 of about 9,855 (261)

Expanding the Phenotype of CYFIP2‐Related Developmental Epileptic Encephalopathy: Case Report and Literature Review

open access: yesAnnals of the Child Neurology Society, Volume 3, Issue 4, Page 314-323, December 2025.
ABSTRACT Background Pathogenic CYFIP2 variants cause developmental and epileptic encephalopathy (DEE), characterized by early‐onset intractable epilepsy and developmental delay. The disease course has not been delineated. Codon Arg87 is a de novo mutational hotspot associated with a severe DEE phenotype via gain‐of‐function mechanisms. Currently, there
Michaela Squire   +3 more
wiley   +1 more source

Experimental substantiation of the expediency of the combined use of piracetam and metformin for pharmacological correction of cognitive disorders in conditions of prolonged hyperglycemia

open access: yesMedičnì Perspektivi, 2020
Chronic hyperglycemia, insulin resistance, endothelial dysfunction, and disturbance of the integrity of the blood-brain barrier are considered as strategically important links in the development of cognitive deficits in diabetic encephalopathy.
А. E. Lievykh   +5 more
doaj   +1 more source

Levetiracetam and Speech Therapy in Aphasia from Penetrating Brain Injury. Could it be the Way To Recovery? [PDF]

open access: yes, 2010
A previously healthy 26 years old right-handed mansustained a penetrating brain injury (PBI) from gunshotwound to the head. The bullet entered the right parietooccipitaljunction, traveled diagonally through the occipitalpole and ended in the left fronto ...
Ayyoub Z, Ben-Youssef R
core  

A New Mathematical Model For Assessment of Memorization Dynamics [PDF]

open access: yes, 2005
Se propone un nuevo modelo de memoria basado en el análisis de regresión y las curvas exponenciales de aprendizaje. La eficacia del modelo se verifica con varios tipos de experimentos incluyendo la aversión a la comida en caracoles, el aprendizaje de ...
Abramson, Charles I., Stepanov, Igor I.
core   +2 more sources

The Concise Guide to PHARMACOLOGY 2025/26: Ion channels

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S152-S241, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +86 more
wiley   +1 more source

Familial adult myoclonus epilepsy: A comprehensive diagnostic strategy for clinical practice

open access: yesEpilepsia, Volume 66, Issue 11, Page 4107-4121, November 2025.
Abstract Familial adult myoclonus epilepsy (FAME) is a genetic neurological disorder characterized by cortical myoclonus and epileptic seizures with clinical features that overlap with other movement disorders and epileptic syndromes, particularly essential tremor (ET), progressive myoclonic epilepsy (PME), and juvenile myoclonic epilepsy (JME).
Yitao Lu   +14 more
wiley   +1 more source

Chronic cerebrovascular diseases: pathogenetic management

open access: yesМедицинский совет, 2016
The article considers the key issues of the clinical pattern, diagnosis and treatment of chronic cerebral ischemia. The results of the observation program "Thiocetam for focal neurological, mild cognitive, asthenic and emotional disorders accompanying ...
I. A. Schukin   +2 more
doaj   +1 more source

New therapeutic activity of metabolic enhancer piracetam in treatment of neurodegenerative disease: Participation of caspase independent death factors, oxidative stress, inflammatory responses and apoptosis.

open access: yesBiochimica et Biophysica Acta - Molecular Basis of Disease, 2018
Piracetam, a nootropic drug that has been clinically used for decades but remains enigmatic due to no distinct understanding of its mechanism of action. The present study aimed to investigate the role of caspase independent pathway in piracetam mediated ...
D. Verma   +12 more
semanticscholar   +1 more source

PENGENDALIAN PERSEDIAAN OBAT GENERIK DENGAN METODE ANALISIS ABC, METODE ECONOMIC ORDER QUANTITY (EOQ), DAN REORDER POINT (ROP) DI APOTEK XYZ TAHUN 2017 [PDF]

open access: yes, 2017
Penelitian ini bertujuan untuk menganalisis pengendalian persediaan obat generik di Apotek XYZ tahun 2017. Data yang digunakan merupakan data primer dan data sekunder.
Dyatmika, Stephanus Bimata
core  

Deep Brain Stimulation in Children and Adolescents with ε‐Sarcoglycan Myoclonus Dystonia Causes a Sustained Improvement in Motor Functionality and Quality of Life

open access: yesMovement Disorders, Volume 40, Issue 10, Page 2234-2242, October 2025.
Abstract Background Deep brain stimulation of the globus pallidus internus (DBS‐GPi) has shown efficacy in adult patients with SGCE‐related myoclonus dystonia. However, evidence regarding its impact in pediatric populations is limited. Objectives The aim was to evaluate motor and non‐motor outcomes following DBS‐GPi intervention in children and ...
Ainara Salazar‐Villacorta   +23 more
wiley   +1 more source

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