Results 91 to 100 of about 2,199 (272)

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

open access: yesAdvanced Science, EarlyView.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou   +8 more
wiley   +1 more source

Comparative evaluation of the length of resin tags, viscosity and microleakage of pit and fissure sealants - an in vitro scanning electron microscope study

open access: yesContemporary Clinical Dentistry, 2011
Introduction : In this era of preventive dentistry, many techniques are available for prevention of caries, such as plaque control, use of systemic and local fluorides and pit and fissure sealants.
A R Prabhakar   +2 more
doaj   +1 more source

Degrading GPX4 via Biomimetic Nanoparticle‐Mediated In Situ Synthesis of Deep‐Learning‐Designed Binder‐Degron Chimeras for Prostate Cancer Therapy

open access: yesAdvanced Science, EarlyView.
A deep‐learning‐designed binder is fused to a combinatorial degron to create a binder‐degron chimera (bdC) that recruits the CUL2‐RING ubiquitin ligase complex. Encapsulation in a prostate‐cancer‐targeted, CD47‐camouflaged nanocarrier enables tumor‐specific in situ bdC expression, triggering GPX4 degradation and ferroptosis, thereby establishing a ...
Si‐Han Zhang   +8 more
wiley   +1 more source

Evaluating Pit and Fissure Sealant Materials When Used as Bonding Agents in Preventive Resin Restorations [PDF]

open access: yes, 2001
Preventive resin restorations (PRR) are an increasingly popular alternative to the traditional amalgam restoration for small occlusal caries in posterior teeth.
Gerber, Paul Shields
core   +1 more source

A comparative study to evaluate the effect of fluoride releasing sealant cured by visible light, argon laers, and light emitting diode curing units: An in vitro study

open access: yesJournal of Indian Society of Pedodontics and Preventive Dentistry, 2009
In Pediatric Dentistry, the use of pit and fissure sealant is one of the essential forms of prevention. Pit and fissure caries may be substantially decreased by obliteration of these developmental defects in occlusal, buccal and lingual surfaces with ...
Das U, Prashanth S
doaj  

The influence of pit and fissure sealants on infrared fluorescence measurements [PDF]

open access: yes, 2008
The aim of this in vitro study was to evaluate the influence of pit and fissure sealants on fluorescence readings using lasers. We selected 166 permanent molars and randomly divided them into 4 groups which were each treated with a different sealant (a ...
Lussi, A.   +12 more
core   +2 more sources

Drug Repurposing for Treating NCOR‐Related Intellectual Disability

open access: yesAdvanced Science, EarlyView.
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong   +15 more
wiley   +1 more source

Fluoride releasing from dental pit and fissure sealant including sodium fluoride and stannous fluoride

open access: yes, 2007
The 2% NaF and 8% SnF2 have been used in topical fluoridation method in the dental office to increase the resistance of enamel to acid dissolution. Bis-GMA based monomers have been used for the basic materials in the dental pit and fissure sealants ...
김광만, 오영일
core   +1 more source

Nonlinear Ion‐Specific Control of Underwater Adhesion by Bottlebrush Polymer Interfaces

open access: yesAdvanced Science, EarlyView.
The efficiency of underwater adhesion is modulated by ion‐specific effects. Strongly hydrated Na+ remains separated from the mica surface by its hydration shell, preserving access to binding sites, whereas weakly hydrated K+ can partially dehydrate and occupy ditrigonal cavities.
Chang‐Sheng Wang   +10 more
wiley   +1 more source

Structure and Function of a Multi‐Megadalton Virus‐Like Proteolytic Dodecahedron

open access: yesAngewandte Chemie, EarlyView.
Zuzalysin, a virulence metallopeptidase of the periodontal pathogen Porphyromonas gingivalis, is secreted as a latent, flexible ≈95‐kDa monomer. Calcium triggers cysteine‐switch activation and hierarchical assembly into pentamers, bipentamers, tripentamers, and a ≈5.6‐MDa, ≈355‐Å dodecahedron. Structures at 1.8–3.6 Å reveal a virus‐sized catalytic cage
Mariusz Madej   +20 more
wiley   +2 more sources

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