Results 201 to 210 of about 2,199 (272)

Engineering Flexible Nanofibrous Hydroxyapatite Scaffolds With Tunable Degradation and Mechanical Properties for Bone Regeneration

open access: yesSmall, EarlyView.
Conventional hydroxyapatite ceramics are brittle and poorly resorbable, limiting their use in bone repair. To overcome these limitations, flexible scaffolds are fabricated using ceramic nanofibers as structural building blocks. Adjusting nanofiber characteristics allows modulating the mechanical properties and degradation, providing a versatile ...
Raúl Agut López   +4 more
wiley   +1 more source

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

open access: yesSmart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang   +8 more
wiley   +1 more source

Peptide Fingerprinting of Single Protein Molecules Using In‐Plane Nanopore Sensors Integrated to an Extended Immobilized Nanoscale Enzymatic Reactor (eINER)

open access: yesSmall Methods, EarlyView.
The protein Time‐of‐Flight (P‐ToF) chip can peptide fingerprint a single protein molecule by subjecting it to a solid phase endopeptidase cleavage reaction in‐line with a combination of resistive pulse sensing of the resulting single peptides and machine‐learning aided identification.
Suresh Shivanka   +7 more
wiley   +1 more source

Microfluidic Molecular Diagnostic Chips: Functional Modules, Integration Strategies, and Emerging Applications

open access: yesSmall Methods, EarlyView.
This comprehensive review delivers an engineering‐centric analysis of microfluidic molecular diagnostic chips, breaking them down into foundational modules from fluid manipulation to bio‐sensing. Beyond chip design, it evaluates sample‐to‐answer integration strategies and commercial readiness levels.
Donghoon Koo   +7 more
wiley   +1 more source

Hydrogen‐Based Reduction of Hematitic Iron Ore in a Fluidized Bed Kinetic Reactor at Elevated Pressures

open access: yessteel research international, EarlyView.
This study investigates the reduction behavior of two international iron ores, including a synthetic hematite produced by oxidation of magnetite, in a novel fluidized‐bed kinetic reactor at elevated pressures. The reduction takes place at various temperatures (650°C, 700°C, and 750°C), and various hydrogen partial pressures (30, 55, and 80 vol% H2 ...
Valentina Nigitz   +5 more
wiley   +1 more source

Progress in Explosion Mechanisms and Prevention Technologies for Direct Chill Casting Aluminum Melt Upon Water Contact: A Review

open access: yesSafety Science and Technology, EarlyView.
Molten aluminum–water explosion triggered by leakage remains the core unresolved safety hazard hindering safe production in aluminum direct chill casting. This review summarizes its explosion mechanism, key influencing factors, prevention technologies, existing gaps, and prospects of intelligent multi‐technology integrated explosion‐proof systems ...
Min Wang   +5 more
wiley   +1 more source

A probabilistic framework for modeling chloride‐induced corrosion and related load‐deformation behaviour of reinforced concrete

open access: yesStructural Concrete, EarlyView.
Abstract Chloride‐exposed reinforced‐concrete structures often suffer localized corrosion, so corrosion initiation time and average steel loss are poor indicators of structural performance. This paper presents a spatially resolved, proof‐of‐concept framework that couples diffusion‐based chloride ingress and initiation with a localized morphology model ...
Deniz Yilmaz, Karel Thoma, Ueli Angst
wiley   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

open access: yesVIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy