Results 61 to 70 of about 742 (244)

Pitchfork bifurcations in blood-cell-shaped dipolar Bose-Einstein condensates [PDF]

Physical Review A, 2010
We demonstrate that the method of coupled Gaussian wave packets is a full-fledged alternative to direct numerical solutions of the Gross-Pitaevskii equation of condensates with electromagnetically induced attractive 1/r interaction, or with dipole-dipole interaction.
Rau, Stefan, Main, Jörg, Köberle, Patrick, Wunner, Günter   +3 more
openaire   +2 more sources

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

Advanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue, Junhao Su, Yiming Chao, Lu Liu, Xinyi Lin, Yang Xiang, Mun Kay Ho, Zezhuo Su, Junyi Chen, Zhuojuan Luo, Chengqi Lin, Ruibang Luo, Theo Aurich, Jianfeng Wu, Kelvin Sin Chi Cheung, Yuanhua Huang, Joshua W. K. Ho, Ryohichi Sugimura   +17 more
wiley   +1 more source

The driven-dissipative Bose–Hubbard dimer: phase diagram and chaos

New Journal of Physics, 2020
We present the phase diagram of the mean-field driven-dissipative Bose–Hubbard dimer model. For a dimer with repulsive on-site interactions ( U  > 0) and coherent driving, we prove that ${{\mathbb{Z}}}_{2}$ -symmetry breaking, via pitchfork bifurcations ...
Andrus Giraldo, Bernd Krauskopf, Neil G R Broderick, Juan A Levenson, Alejandro M Yacomotti   +4 more
doaj   +1 more source

Dual Aptamers‐Based SETDB1 PROTACs as Effective Anti‐Tumor Strategies for Breast Cancer

Advanced Science, EarlyView.
This study establishes dual‐aptamer PROTACs targeting SETDB1 using a SETDB1‐specific aptamer conjugated to AS1411. The designed PROTACs penetrate cells, recruit MDM2 to degrade SETDB1, and inhibit cancer cell proliferation and migration. Remarkably, they also overcome tamoxifen resistance and enhance CD8+ T cell cytotoxicity, suppressing tumor growth ...
Yanxuan Guo, Yingge Lv, Shuyu Huang, Chang Liu, Yan Ouyang, Bei Lan, Chenghao Xuan   +6 more
wiley   +1 more source

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

Advanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang, Wanyi Xiao, Hongru Shen, Fenge Li, Ting Li, Weihong Zhang, Haotian Liu, Ziwei Gao, Hongyu Wang, Xiubao Ren, Kexin Chen, Xiangchun Li, Jilong Yang   +12 more
wiley   +1 more source

Nanozyme Microrobots: Programmable Spatiotemporal Catalysis for Targeted Therapy and Diagnostics

Advanced Science, EarlyView.
This review presents nanozyme microrobots as emerging catalytic systems that integrate mobility, external actuation, and adaptive reactivity to achieve precise biochemical functions. By examining mobility‐regulated catalysis, spatial targeting, integrated designs, and translational demonstrations, the article highlights how nanozyme robotics enables ...
Hong Huy Tran, Nil Kanatha Pandey, David P. Cormode, Daeyeon Lee, Edward Steager, Hyun Koo   +5 more
wiley   +1 more source

Nonlinear Magnetoconvection in a Sparsely Packed Porous Medium

International Journal of Geophysics, 2011
Linear and weakly nonlinear properties of magnetoconvection in a sparsely packed porous medium are investigated. We have obtained the values of Takens-Bogdanov bifurcation points and codimension two bifurcation points by plotting graphs of neutral curves
A. Benerji Babu, Ragoju Ravi, S. G. Tagare   +2 more
doaj   +1 more source

Revising Fascial Anatomy With a Focus on the Fusion Fascia in Mesenteric Gastrointestinal Cancer Surgery

Annals of Gastroenterological Surgery, EarlyView.
This review critically reassesses our prior hypothesis and proposes a revised anatomical model of the fusion fascia that is broadly applicable to GI cancer surgeries grounded in the principles of mesenteric resection. Our synthesis suggests that the fusion fascia is neither a dense connective tissue membrane nor a remnant of mesothelial fusion, but ...
Hisashi Shinohara, Yasunori Kurahashi, Jun Watanabe, Yuichi Nagakawa, Tatsuro Nakamura, Eiichiro Nakao, Yudai Hojo, Shugo Kohno, Motoki Murakami, Yoshinori Ishida   +9 more
wiley   +1 more source

Bifurcation analysis and dynamics of a Lorenz –type dynamical system

پژوهش‌های ریاضی, 2017
./files/site1/files/0Abstract1.pdfIn this paper we consider a continues Lorenz – type dynamical system. Dynamical behaviors of this system such as computing equilibrium points, different bifurcation curves and computation of normal form coefficient of ...
Behnaz Rahmani, Reza Khoshsiar, Mohammad ShfieDehaghin, Neda Ahanjideh   +3 more
doaj  

Bogdanov-Takens bifurcations in the enzyme-catalyzed reaction comprising a branched network

Mathematical Biosciences and Engineering, 2017
There have been some results on bifurcations of codimension one (such as saddle-node, transcritical, pitchfork) and degenerate Hopf bifurcations for an enzyme-catalyzed reaction system comprising a branched network but no further discussion for ...
Qiuyan Zhang, Lingling Liu, Weinian Zhang   +2 more
doaj   +1 more source