Results 51 to 60 of about 61,503 (311)
Water‐Soluble Molecular Wires for Membrane Potential Imaging
Fully water‐soluble fluorescent rosamine‐based amphiphilic molecular wires were developed for imaging membrane potentials. The performance of the probes was evaluated in single cardiomyocytes, murine pituitary gland, and islets of Langerhans.
Mirna El Khatib+9 more
wiley +2 more sources
Developmental and functional effects of steroid hormones on the neuroendocrine axis and spinal cord [PDF]
This review highlights the principal effects of steroid hormones at central and peripheral levels in the neuroendocrine axis. The data discussed highlight the principal role of oestrogens and testosterone in hormonal programming in relation to sexual ...
Gonzalez Deniselle, Maria Claudia+4 more
core +2 more sources
Genome‐wide analyses indicate that reduced ventral diencephalon and thalamus volumes, along with decreased functional connectivity within the triple network (DMN/CEN/SN), are uniquely associated with the risk of major depression (MD) onset, compared to other similar severe psychiatric disorders.
Ming‐Min Xu+7 more
wiley +1 more source
Pituitary Adenomas: From Diagnosis to Therapeutics
Pituitary adenomas are tumors that arise in the anterior pituitary gland. They are the third most common cause of central nervous system (CNS) tumors among adults.
Samridhi Banskota, David C. Adamson
doaj +1 more source
Acromegaly: pathogenesis & treatment [PDF]
Acromegaly is a multi-system disorder whose etiology is most often traced back to a growth hormone-secreting pituitary adenoma (PA). Growth hormone (GH) secretion promotes insulin-like growth factor 1 (IGF-1) release from peripheral tissues, leading to ...
Tilvawala, Megha
core
Influence of mirtazapine on salivary cortisol in depressed patients [PDF]
Unlike other antidepressants, mirtazapine does not inhibit the reuptake of norepinephrine or serotonin but acts as an antagonist at presynaptic alpha(2)-receptors, at postsynaptic 5-HT2 and 5-HT3 receptors, and at histaminergic H1 receptors. Furthermore,
Baghai, Thomas C.+3 more
core +1 more source
Genomic Insights into the Origin, High Fecundity and Environmental Adaptation of Hu Sheep
The Hu sheep diverged from the Small‐tailed Han sheep ≈1330 years ago, and subsequently migrated from northern to warm and humid southern regions. The genes BMPR1B, UNC5C, and GRID2 play a synergistic role in the superior reproductive traits of Hu sheep.
Zexuan Liu+12 more
wiley +1 more source
Nitric oxide-sensitive guanylyl cyclase is differentially regulated by nuclear and non-nuclear estrogen pathways in anterior pituitary gland. [PDF]
17β-estradiol (E2) regulates hormonal release as well as proliferation and cell death in the pituitary. The main nitric oxide receptor, nitric oxide sensitive- or soluble guanylyl cyclase (sGC), is a heterodimer composed of two subunits, α and β, that ...
Jimena P Cabilla+5 more
doaj +1 more source
Soluble guanylyl cyclase α1 subunit is a key mediator of proliferation, survival, and migration in ECC-1 and HeLa cell lines [PDF]
Soluble guanylyl cyclase (sGC) is a heterodimeric enzyme constituted by two subunits, α1 and β1. Previously we have shown that 17β-estradiol (E2) exerts opposite effects on these subunits by increasing α1 and decreasing both β1 expression and enzymatic ...
Bollani, Sabrina Natalia+6 more
core +1 more source
Inspired by the prolactin secretion profile under normal physiological conditions, biomimetic prolactin‐releasing microneedles are designed. Under the control of near infrared (NIR), these responsive microneedles facilitate pulsed release of prolactin to inhibit fatty liver formation.
Hongli Yin+6 more
wiley +1 more source