Results 271 to 280 of about 241,755 (405)

Crosstalk between thyroid hormones and the central corticotropin‐releasing factor system in Atlantic salmon

open access: yesJournal of Neuroendocrinology, EarlyView.
The corticotropin‐releasing factor (CRF) system plays a key role in centrally regulating thyroid hormone (TH) synthesis in non‐mammalian vertebrates, but interactions between THs and the CRF system remain poorly understood in fish. Here, we report that THs directly affect transcription of several CRF system components across different hypophysiotropic ...
Brett M. Culbert   +2 more
wiley   +1 more source

Loss of choroid plexus‐derived insulin‐like growth factor 2 (IGF2) leads to hyposmia, while retaining post‐partum mood resilience in mice

open access: yesJournal of Neuroendocrinology, EarlyView.
Abstract During the post‐partum period, new mothers are vulnerable to mood disorders. In adults, impairments in neurogenesis commonly associate with anxiety and depressive behaviors. Insulin‐like growth factor 2 (IGF2) is expressed in the choroid plexus (CP) within the subventricular zone (SVZ) neurogenic niche, and global loss of IGF2 leads to ...
Hollian R. Phillipps   +4 more
wiley   +1 more source

The 20 kDa isoform of the human growth hormone variant alters adipose and muscle gene expression differently than human growth hormone

open access: yesJournal of Neuroendocrinology, EarlyView.
Abstract The 20 kDa isoform of human growth hormone variant (20K hGH‐V) (derived from the GH2 gene) has previously been shown to promote growth but lacks the diabetogenic and lactogenic activities of human GH (derived from the GH1 gene). That is, 20K hGH‐V‐treated mice have similar body size and composition to hGH‐treated mice, as well as improved ...
Jonathan A. Young   +7 more
wiley   +1 more source

Pituitary cells in man during aging: An immunohistological and morphometric study. [PDF]

open access: yesJ Med Biochem
Čukuranović-Kokoris J   +3 more
europepmc   +1 more source

Cholecystokinin: Clinical aspects of the new biology

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Cholecystokinin (CCK) is a classic gut hormone that has been known for almost a century to regulate gallbladder emptying, pancreatic enzyme secretion, and gastrointestinal motor activity. In 1968, the CCK structure was identified by Viktor Mutt and Erik Jorpes from porcine gut extracts as a peptide of 33 amino acid residues.
Jens F. Rehfeld
wiley   +1 more source

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