Results 271 to 280 of about 248,144 (357)

Growth hormone releasing factor increases growth hormone release from MtTW15 pituitary tumors

Brain Research, 1984
The MtTW15 pituitary tumor secretes growth hormone and prolactin. Perfusion of these dispersed MtTW15 tumor cells with 10 nM growth hormone releasing factor (GRF) increases growth hormone release without affecting prolactin release. This effect is dose-dependent between 0.001 and 0.1 nM and is blocked by 100 nM somatostatin. These findings suggest that
A M, Judd, R M, MacLeod
openaire   +2 more sources

Factors Influencing Pituitary Glycogen Metabolism and Gonadotropic Hormone Release. I. Luteinizing Hormone-Releasing Hormone

Fertility and Sterility, 1974
The way in which luteinizing hormone (LH) and follicle stimulating h ormone (FSH) are related to pituitary glycogen metabolism is investigated by measuring pituitary glycogen content and the activity of glycogen synthetase and glycogen phosphorylase in LH-releasing hormone (LH-RH) treated rat pituitaries.
T, Makino, L M, Demers, R O, Greep
openaire   +2 more sources

Modelling the Pituitary Response to Luteinizing Hormone‐Releasing Hormone

Journal of Neuroendocrinology, 2004
AbstractThe pituitary response to luteinizing hormone‐releasing hormone (LHRH) is steroid‐dependent and varies throughout the reproductive cycle, but the rapid rise in pituitary sensitivity on the day of the ovulation‐inducing LH surge is due to a ‘self‐priming’ effect of exposure to LHRH that results in a potentiation of pituitary responsiveness 35–40 
S, Scullion, D, Brown, G, Leng
openaire   +2 more sources

Effects of cholinergic stimulation on pituitary hormone release

Psychoneuroendocrinology, 1982
Abstract Physostigmine was infused into human volunteers to assess the effect of central cholinergic stimulation on memory and on neuroendocrine function. Methscopolamine bromide, a peripheral anticholinergic agent, was given simultaneously. The lower dose of physostigmine (1.0 mg) produced no change in AVP, cortisol, melatonin, GH or LH in those ...
B M, Davis, G M, Brown, M, Miller, H G, Friesen, A J, Kastin, K L, Davis   +5 more
openaire   +2 more sources

Stimulation of luteinizing hormone release from chicken pituitary cells by analogues of luteinizing hormone-releasing hormone

General and Comparative Endocrinology, 1977
The luteinizing hormone (LH) releasing activities of luteinizing hormone-releasing hormone (LH-RH) and four related analogues were compared using isolated chicken anterior pituitary cells. The analogues, des-Gly10-LH-RH and Phe5-LH-RH, exhibited a greater potency than LH-RH (150 and 237%, respectively), whereas LH-RH(OH) was much less active (1.1 ...
R C, Bonney, F J, Cunningham
openaire   +2 more sources

Cortisol inhibition of growth hormone-releasing hormone-stimulated growth hormone release from cultured sheep pituitary cells

Journal of Endocrinology, 1994
Abstract Cortisol inhibits growth hormone (GH) release in short-term culture and is stimulatory in long-term cultures of rat and human pituitary cells. This study sought to determine the in vitro effects of cortisol on GH release and the signal transduction pathways mediating the effects of cortisol on GH release from cultured ovine ...
J L, Sartin, R J, Kemppainen, E S, Coleman, B, Steele, J C, Williams   +4 more
openaire   +2 more sources

Quantitative immunocytochemistry of pituitary receptors for luteinizing hormone-releasing hormone

Cell and Tissue Research, 1975
In Araldite sections of male rat pituitaries, stained after embedding by the unlabeled antibody enzyme method with antisera to native luteinizing hormone-releasing hormone (LH-RH) or LH-RH azo-conjugated to bovine serum albumin, localization is confined mainly to the interior of the large, and to a lesser extent to that of the small, secretion granules
L A, Sternberger, J P, Petrali
openaire   +2 more sources

Growth hormone-releasing hormone transcripts in human pituitary adenomas.

The Journal of Clinical Endocrinology & Metabolism, 1992
We have investigated the possibility that local production of GHRH within the adenohypophysis could be an aetiological factor in the development of human pituitary somatotroph and other tumours. We examined 51 human pituitary adenomas for GHRH transcripts using in situ hybridization histochemistry.
A, Levy, S L, Lightman
openaire   +3 more sources

Growth hormone-releasing hormone and pituitary development, hyperplasia and tumorigenesis

Trends in Endocrinology & Metabolism, 2002
Growth hormone-releasing hormone (GHRH) is essential for expansion of the somatotrope lineage during pituitary development, and excessive GHRH secretion and/or action results in unregulated somatotrope proliferation and neoplastic transformation. Our understanding of the molecular and morphological bases for these effects from both animal and clinical ...
Lawrence A, Frohman, Rhonda D, Kineman
openaire   +2 more sources

Sexual dimorphic porcine pituitary response to growth hormone-releasing hormone

Domestic Animal Endocrinology, 1990
The aim of this study was to compare growth hormone (GH) response of barrows and gilts to porcine growth hormone-releasing hormone (pGRH) at the pituitary level. Anterior pituitary cells from barrows and gilts responded to pGRH in a dose-dependent manner.
M L, Heiman, P L, Surface, D H, Mowrey, R D, DiMarchi   +3 more
openaire   +2 more sources