Results 321 to 330 of about 241,755 (405)

Two pools of luteinizing hormone in the human pituitary: evidence from constant administration of luteinizing hormone-releasing hormone.

Journal of Clinical Endocrinology and Metabolism, 1974
The pituitary gonadotrophin response to constant intravenous infusions of hypothalamic luteinizing hormone-releasing hormone (LH-RH), 0.2 μg/min for 4 hr, was studied in 5 normal human men.
W. J. Bremner, C. Paulsen
semanticscholar   +1 more source

Growth hormone-releasing hormone and pituitary development, hyperplasia and tumorigenesis

Trends in Endocrinology & Metabolism, 2002
Growth hormone-releasing hormone (GHRH) is essential for expansion of the somatotrope lineage during pituitary development, and excessive GHRH secretion and/or action results in unregulated somatotrope proliferation and neoplastic transformation. Our understanding of the molecular and morphological bases for these effects from both animal and clinical ...
Rhonda D. Kineman, Lawrence A. Frohman
openaire   +3 more sources

Pituitary adenomas in mice transgenic for growth hormone-releasing hormone.

Endocrinology, 1992
It has been shown that mice transgenic for human GH-releasing hormone (GRH) develop hyperplasia of pituitary somatotrophs, lactotrophs, and mammosomatotrophs, cells capable of producing both GH and PRL, by 8 months of age. We now report that GRH transgenic mice 10-24 months of age develop pituitary adenomas, which we characterized by histology ...
Asa, S L, Kovacs, K, Stefaneanu, L, Horvath, E, Billestrup, Nils, Gonzalez-Manchon, C, Vale, W   +6 more
openaire   +4 more sources

Identification of luteinizing hormone-releasing hormone (LH-RH) in the brain and pituitary gland of a fish by immunocytochemistry.

The Journal of experimental zoology, 1979
For the first time immunoreactive luteinizing hormone-releasing hormone (LH-RH) is demonstrated in both the brain and pituitary gland of a teleost (Xiphophorus maculatus) using an immunoperoxidase procedure.
M. Schreibman, Leslie R. Halpern, H. Goos, H. Margolis-Kazan   +3 more
semanticscholar   +1 more source

Effect of hydrocortisone on the pituitary response to growth hormone releasing hormone

Psychopharmacology, 2000
In depression, the growth hormone (GH) response to clonidine and L-tryptophan (L-TRP) is reduced, suggesting reduced alpha2-adrenergic and serotonin (5-HT)1A receptor function. Pretreatment with hydrocortisone (100 mg, orally 11 h before) also blunts the GH response to L-TRP.
Stuart Watson, A. H. Young, Porter Rj
openaire   +4 more sources

Body weight and the pituitary response to hypothalamic releasing hormones in patients with anorexia nervosa.

Journal of Clinical Endocrinology and Metabolism, 1976
Fifteen women with anorexia nervosa were studied before and after weight gain. Basal plasma thyroid stimulating hormone (TSH) and prolactin (PRL), and the responses of both these hormones to thyrotropin releasing hormone (TRH), were normal.
P. Beumont, G. C. George, B. Pimstone, A. Vinik   +3 more
semanticscholar   +1 more source

Immunocytochemistry of a ?private? luteinizing-hormone-releasing hormone system in the pituitary

Cell and Tissue Research, 1984
Immunocytochemistry of paraffin sections of Bouin-fixed rat pituitaries with antiserum to luteinizing-hormone-releasing hormone (LHRH) revealed two types of cells. Type I cells exhibit granular staining throughout their cytoplasm. The immunoreactivity of type II cells is confined to a much smaller area of the cytoplasm.
Ludwig A. Sternberger, J. Yuan Li, Richard J. Knapp   +2 more
openaire   +3 more sources

Stimulation of luteinizing hormone release from chicken pituitary cells by analogues of luteinizing hormone-releasing hormone

General and Comparative Endocrinology, 1977
The luteinizing hormone (LH) releasing activities of luteinizing hormone-releasing hormone (LH-RH) and four related analogues were compared using isolated chicken anterior pituitary cells. The analogues, des-Gly10-LH-RH and Phe5-LH-RH, exhibited a greater potency than LH-RH (150 and 237%, respectively), whereas LH-RH(OH) was much less active (1.1 ...
F. J. Cunningham, Rosemary C. Bonney
openaire   +3 more sources

Rapid sequential intravenous administration of four hypothalamic releasing hormones as a combined anterior pituitary function test in normal subjects.

Journal of Clinical Endocrinology and Metabolism, 1985
Normal subjects were studied to test the feasibility of a combined anterior pituitary function test using iv administration of four hypothalamic releasing hormones: ovine corticotropin-releasing hormone, human GH-releasing hormone, GnRH, and TRH ...
W R Sheldon, C. Debold, William S. Evans, G. Decherney, G. Decherney, R. Jackson, R. Jackson, D. Island, M. O. Thorner, David N. Orth   +9 more
semanticscholar   +1 more source

Factors Influencing Pituitary Glycogen Metabolism and Gonadotropic Hormone Release. I. Luteinizing Hormone-Releasing Hormone

Fertility and Sterility, 1974
The way in which luteinizing hormone (LH) and follicle stimulating h ormone (FSH) are related to pituitary glycogen metabolism is investigated by measuring pituitary glycogen content and the activity of glycogen synthetase and glycogen phosphorylase in LH-releasing hormone (LH-RH) treated rat pituitaries.
Roy O. Greep, Tsunehisa Makino, Laurence M. Demers   +2 more
openaire   +3 more sources