Results 111 to 120 of about 3,259,919 (360)

Single-cell transcriptomics reveal distinct immune-infiltrating phenotypes and macrophage–tumor interaction axes among different lineages of pituitary neuroendocrine tumors

Genome Medicine
Background Pituitary neuroendocrine tumors (PitNETs) are common gland neoplasms demonstrating distinctive transcription factors. Although the role of immune cells in PitNETs has been widely recognized, the precise immunological environment and its ...
Shaojian Lin, Yuting Dai, Changxi Han, Tianyi Han, Linfeng Zhao, Renyan Wu, Jianyue Liu, Bo Zhang, Ning Huang, Yanting Liu, Shujing Lai, Jintong Shi, Yu Wang, Meiqing Lou, Jing Xie, Yijun Cheng, Hao Tang, Hong Yao, Hai Fang, Yan Zhang, Xuefeng Wu, Lei Shen, Youqiong Ye, Li Xue, Zhe Bao Wu   +24 more
doaj   +1 more source

E-cadherin expression is associated with somatostatin analogue response in acromegaly [PDF]

, 2018
Acromegaly is a rare disease resulting from hypersecretion of growth hormone (GH) and insulin‐like growth factor 1 (IGF1) typically caused by pituitary adenomas, which is associated with increased mortality and morbidity. Somatostatin analogues (SSAs)
Cano, David A., Castaño, Justo P., Dios, Elena, Flores Martínez, Álvaro, Ibáñez Costa, Alejandro, Japón Rodríguez, Miguel Ángel, Luque, Raúl M., Madrazo Atutxa, Ainara, Soto Moreno, Alfonso Manuel, Venegas Moreno, Eva, Vázquez Borrego, Mari C.   +10 more
core   +1 more source

Enhanced Performance of Brain Tumor Classification via Tumor Region Augmentation and Partition

PLoS ONE, 2015
Automatic classification of tissue types of region of interest (ROI) plays an important role in computer-aided diagnosis. In the current study, we focus on the classification of three types of brain tumors (i.e., meningioma, glioma, and pituitary tumor ...
Jun Cheng, Wei Huang, S. Cao, Ru Yang, Wei Yang, Zhaoqiang Yun, Zhijian Wang, Qianjin Feng   +7 more
semanticscholar   +1 more source

Ontogeny of RSPO1, FOXL2, and RUNX1 during ovarian differentiation in the marsupial tammar wallaby

Developmental Dynamics, EarlyView.
Abstract Background RSPO1 and FOXL2 are female sex‐determining genes involved in the differentiation and organization of the ovary in some eutherian mammals. Mutations or loss of function of these genes are associated with partial to full sex reversal in mice, humans, and goats.
Monika R. Paranjpe, Yu Chen, Geoff Shaw, Marilyn B. Renfree   +3 more
wiley   +1 more source

X-linked ubiquitin-specific peptidase 11 (USP11) increases susceptibility to Cushing’s disease in women

Acta Neuropathologica Communications
The incidence of pituitary adrenocorticotropic hormone (ACTH)-secreting PitNETs, commonly known as ACTH PitNETs, is significantly higher in females; however, the underlying causes for this gender disparity remain unclear.
Tao Zhang, Yanting Liu, Fang Liu, Kaiyu Guo, Runhua Tang, Jingwei Ye, Li Xue, Zhipeng Su, Zhe Bao Wu   +8 more
doaj   +1 more source

Carotid Endarterectomy Ameliorates Cognitive Impairment in Clinical and Experimental Unilateral Carotid Artery Stenosis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Carotid endarterectomy (CEA) is widely used to treat carotid artery stenosis (CAS). However, the effects of CEA on unilateral CAS‐induced cognitive impairment and the underlying mechanism remain poorly understood.
Yijun Cheng, Bin Chen, Miao Zhang, Zhenghong Chen, Mingjian Liu, Ziqian Zhang, Hao Tang, Dapeng Wang, Wenwen Lv, Biao Li, Yuting Dai, Hanbing Shang   +11 more
doaj   +1 more source

Characterization of Human Pituitary Adenomas in Cell Cultures by Light And Electron Microscopic Morphology And Immunolabeling [PDF]

, 2005
The morphology and hormone production of pituitary adenoma cell cultures were compared in order to highlight their characteristic in vitro features. Cell suspensions were prepared from 494 surgical specimens.
Bácsy, Ernő, Bálint, Katalin, Fazekas, Ilona, Hegedűs, Balázs, Kerekes, Edit, Pásztor, Emil, Slowik, Felicia   +6 more
core  

The Molecular Pathogenesis of Pituitary Adenomas: An Update [PDF]

, 2013
Pituitary tumors represent the most common intracranial neoplasms accompanying serious morbidity through mass effects and inappropriate secretion of pituitary hormones. Understanding the etiology of pituitary tumorigenesis will facilitate the development
Jiang, Xiaobing, Zhang, Xun
core   +2 more sources

Pituitary neuroendocrine tumors: a model for neuroendocrine tumor classification

Modern Pathology, 2021
S. Asa, O. Mete, M. Cusimano, I. McCutcheon, A. Perry, S. Yamada, H. Nishioka, O. Casar-Borota, S. Uccella, S. La Rosa, A. Grossman, S. Ezzat, Sofia Süheyla Uyar Nil Giulia Peter Nuperi Richard A. Hi Asioli Bozkurt Comunoglu Cossu Earls Gazioglu Hick, S. Asioli, S. Bozkurt, N. Çomunoğlu, G. Cossu, P. Earls, Nuperi Gazioglu, R. A. Hickman, H. Ikeda, E. Manojlović-Gačić, M. Messerer, B. Öz, Sara Pakbaz, F. Roncaroli, W. Saeger, J. Turchini, S. Yarman   +28 more
semanticscholar   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source