Results 131 to 140 of about 3,292,689 (405)

Efficacy, safety, and relapse outcomes of MAPK inhibitors in pediatric Langerhans cell histiocytosis: A real‐world study

open access: yesInternational Journal of Cancer, EarlyView.
What's new? Mitogen‐activated protein kinase (MAPK) inhibitors are promising treatments for pediatric Langerhans cell histiocytosis (LCH), a rare heterogeneous neoplasm that often affects multiple organ systems. Which MAPK inhibitors are most effective against LCH remains uncertain.
Xue Tang   +5 more
wiley   +1 more source

Outcome of endoscopy-assisted microscopic extended transsphenoidal surgery for suprasellar craniopharyngiomas

open access: yesFrontiers in Endocrinology, 2012
Objectives. Craniopharyngiomas are difficult to treat. The extended transsphenoidal approach has recently been described in several small series. We describe the usefulness of microscopy-assisted angled endoscopy for visualizing vital structures such as ...
Hidetoshi eIkeda
doaj   +1 more source

The Molecular Pathogenesis of Pituitary Adenomas: An Update [PDF]

open access: yes, 2013
Pituitary tumors represent the most common intracranial neoplasms accompanying serious morbidity through mass effects and inappropriate secretion of pituitary hormones. Understanding the etiology of pituitary tumorigenesis will facilitate the development
Jiang, Xiaobing, Zhang, Xun
core   +2 more sources

Erratum to: The Clinical Utility of TIMP3 Expression in ACTH-Secreting Pituitary Tumor [PDF]

open access: bronze, 2016
Bowen Sun   +12 more
openalex   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

open access: yesiNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

Pituitary metastases as a rare variant of intracranial metastasis

open access: yesБюллетень сибирской медицины, 2008
Metastatiс spread of neoplasms to the pituitary gland is a relatively common finding in autopsy series of cancer patients. The majority of these patients were asymptomatic.
A. V. Osnitskaya, V. Ye. Olyushin
doaj   +1 more source

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

open access: yesInterdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang   +6 more
wiley   +1 more source

Effects of Low versus Intermediate Doses of Dexmedetomidine Infusion on Blood Loss, Hemodynamics, and Operative Time in Transsphenoidal Pituitary Tumor Removal: A Prospective Randomized Study [PDF]

open access: diamond, 2023
Saipin Muangman   +6 more
openalex   +1 more source

Effect of Epigallocatechin‐3‐Gallate on Depression‐Related Cytokines in Thalassemia Patients: Molecular and Cellular Evaluation

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study investigates the effects of Epigallocatechin‐3‐Gallate (EGCG), a potent anti‐inflammatory polyphenol isolated from Winged Marigold, on cytokine expression linked to depression in β‐thalassemia patients. EGCG demonstrated dose‐dependent suppression of key inflammatory cytokines (IL‐6, IL‐1β, TNF‐α, IFN‐γ) at both gene and protein levels ...
Mohammed N. Salman   +5 more
wiley   +1 more source

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