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2005
Few human pituitary tumor cell lines have been established. This scarcity may be related to the fact that hormone production rapidly declines within weeks to months after initiation of the culture. In addition, the number of proliferating cells in pituitary adenomas is very low.
Hofland, Leo, Lamberts, S.W.J.
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Few human pituitary tumor cell lines have been established. This scarcity may be related to the fact that hormone production rapidly declines within weeks to months after initiation of the culture. In addition, the number of proliferating cells in pituitary adenomas is very low.
Hofland, Leo, Lamberts, S.W.J.
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Pathology - Research and Practice, 1988
Pituitary malignancies are rare. The definition of pituitary malignancy is still subject to debate. Three types of malignancy with the description of clinical course and complete autopsy were presented; i) true carcinosarcoma, ii) ectopic sphenoid invasive tumor, and iii) post-irradiation sarcoma.
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Pituitary malignancies are rare. The definition of pituitary malignancy is still subject to debate. Three types of malignancy with the description of clinical course and complete autopsy were presented; i) true carcinosarcoma, ii) ectopic sphenoid invasive tumor, and iii) post-irradiation sarcoma.
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Hormone Research in Paediatrics, 2007
<i>Background:</i> Pituitary tumors are common and usually grow insidiously over many years. Rarely fatal, treatment still requires multiple cytoreductive surgeries and/or radiation therapy with its attendant side effects. As a disease process of regulatory pathways, pituitary tumors offer numerous potential therapeutic targets, and many ...
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<i>Background:</i> Pituitary tumors are common and usually grow insidiously over many years. Rarely fatal, treatment still requires multiple cytoreductive surgeries and/or radiation therapy with its attendant side effects. As a disease process of regulatory pathways, pituitary tumors offer numerous potential therapeutic targets, and many ...
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2014
Pituitary adenomas are benign intracranial neoplasms that present a major clinical concern due to hormone overproduction and/or tumor mass effects. The majority of pituitary adenomas occur sporadically; however, familial cases are increasingly being recognized, such as multiple endocrine neoplasia type 1 (MEN1), Carney complex (CNC), and familial ...
Neda, Alband, Márta, Korbonits
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Pituitary adenomas are benign intracranial neoplasms that present a major clinical concern due to hormone overproduction and/or tumor mass effects. The majority of pituitary adenomas occur sporadically; however, familial cases are increasingly being recognized, such as multiple endocrine neoplasia type 1 (MEN1), Carney complex (CNC), and familial ...
Neda, Alband, Márta, Korbonits
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2019
Pituitary adenomas represent a common intracranial pathology, usually resulting in the systemic secretion of hormones and compression of local endocrine and optic structures, causing a wide variety of clinical sequelae. While they are typically treated with upfront endocrine and/or surgical decompressive therapy, in patients with residual, recurrent ...
Daniel M, Trifiletti +3 more
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Pituitary adenomas represent a common intracranial pathology, usually resulting in the systemic secretion of hormones and compression of local endocrine and optic structures, causing a wide variety of clinical sequelae. While they are typically treated with upfront endocrine and/or surgical decompressive therapy, in patients with residual, recurrent ...
Daniel M, Trifiletti +3 more
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Endocrinology and Metabolism Clinics of North America, 1987
Nonfunctioning pituitary adenomas represent approximately 25 per cent of all clinically apparent pituitary tumors. The tumors are usually macroadenomas and present with symptoms caused by mass effect or hypopituitarism. In addition to structural studies and assessment of pituitary hormone function, all patients with clinically nonfunctioning tumors ...
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Nonfunctioning pituitary adenomas represent approximately 25 per cent of all clinically apparent pituitary tumors. The tumors are usually macroadenomas and present with symptoms caused by mass effect or hypopituitarism. In addition to structural studies and assessment of pituitary hormone function, all patients with clinically nonfunctioning tumors ...
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Nonfunctioning pituitary tumors
2014Clinically nonfunctioning adenomas range from being completely asymptomatic, and therefore detected either at autopsy or as incidental findings on head MRI or CT scans performed for other reasons, to causing significant hypothalamic/pituitary dysfunction and visual field compromise due to their large size.
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Pituitary tumors and pregnancy
Growth Hormone & IGF Research, 2003Tumors vary in how they affect pregnancy depending upon the hormone secreted. Some hormone oversecretion syndromes must be controlled to allow pregnancy to proceed without undue maternal and fetal morbidity (Cushing's disease and hyperthyroidism) whereas treatment during pregnancy for other tumors is not necessary.
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PATHOGENESIS OF PITUITARY TUMORS
Endocrinology and Metabolism Clinics of North America, 1999Pituitary adenomas may hypersecrete hormones (including prolactin, growth hormone and adrenocorticotropic hormone, and rarely follicle-stimulating hormone, luteinizing hormone or TSH) or may be nonfunctional. Despite their high prevalence in the general population, these tumors are invariably benign and exhibit features of differentiated pituitary cell
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