Results 111 to 120 of about 110,519 (362)

Pituitary Tumors [PDF]

open access: yesCA: A Cancer Journal for Clinicians, 1976
D A, Ontjes, R L, Ney
openaire   +2 more sources

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

open access: yesIbrain, EarlyView.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard   +2 more
wiley   +1 more source

Mutation analysis of inhibitory guanine nucleotide binding protein alpha (GNAI) loci in young and familial pituitary adenomas.

open access: yesPLoS ONE, 2014
Pituitary adenomas are neoplasms of the anterior pituitary lobe and account for 15-20% of all intracranial tumors. Although most pituitary tumors are benign they can cause severe symptoms related to tumor size as well as hypopituitarism and/or ...
Hande Demir   +6 more
doaj   +1 more source

Efficacy, safety, and relapse outcomes of MAPK inhibitors in pediatric Langerhans cell histiocytosis: A real‐world study

open access: yesInternational Journal of Cancer, EarlyView.
What's new? Mitogen‐activated protein kinase (MAPK) inhibitors are promising treatments for pediatric Langerhans cell histiocytosis (LCH), a rare heterogeneous neoplasm that often affects multiple organ systems. Which MAPK inhibitors are most effective against LCH remains uncertain.
Xue Tang   +5 more
wiley   +1 more source

Case Report: Collision tumors of the sellar region: pituitary adenoma and chordoma coexist in the sellar region

open access: yesFrontiers in Endocrinology
Collision tumors are relatively rare and refer to the coexistence of distinct tumors in the same anatomical region, where they invade each other. Sellar collision tumors are especially uncommon.
Shuo Gao   +7 more
doaj   +1 more source

AIP and MEN1 mutations and AIP immunohistochemistry in pituitary adenomas in a tertiary referral center. [PDF]

open access: yes, 2019
Background: Pituitary adenomas have a high disease burden due to tumor growth/ invasion and disordered hormonal secretion. Germline mutations in genes such as MEN1 and AIP are associated with early onset of aggressive pituitary adenomas that can be ...
Cano González, David A.   +2 more
core  

Hypervision Proton Surgery: The Future Direction of Proton Therapy

open access: yesiNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

A multi-disciplinary team model based on CBL in clinical teaching of hypothalamus-pituitary diseases [PDF]

open access: yesJichu yixue yu linchuang, 2020
Objective To explore the effect of case-based learning (CBL) combined with hypothalamus-pituitary MDT clinic in clinical teaching of hypothalamus pituitary diseases. Methods The trainees who participated in the hypothalamus-pituitary MDT discussion and
DUAN Lian, ZHENG Guang-yao, LU Lin, ZHU Hui-juan, YAO Yong, PAN Hui
doaj  

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

open access: yesInterdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang   +6 more
wiley   +1 more source

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