Results 111 to 120 of about 3,206,200 (405)

EPMA position paper in cancer:current overview and future perspectives [PDF]

, 2015
At present, a radical shift in cancer treatment is occurring in terms of predictive, preventive, and personalized medicine (PPPM). Individual patients will participate in more aspects of their healthcare.
Bubnov, Rostylav, Danesi, Romano, Desiderio, Dominic M., Grech, Godfrey, Hagan, Suzanne, Vittadini, Giorgio, Yoo, Byong Chul, Zhan, Xianquan   +7 more
core   +5 more sources

The epidemiology and management patterns of pediatric pituitary tumors in the United States

Pituitary, 2021
L. Castellanos, M. Misra, T. Smith, E. Laws, J. Iorgulescu   +4 more
semanticscholar   +1 more source

Nephroprotective Potential of Olea europaea Leaf Extract Against Combined Noise and Toluene‐Induced Oxidative and Histopathological Renal Injuries in Wistar Rats

Chemistry &Biodiversity, EarlyView.
ABSTRACT Noise and toluene are environmental stressors that induce oxidative stress and inflammation, contributing to renal dysfunction. This study evaluated the protective effects of Olea europaea leaf extract (OeLE; 40 mg/kg/day) against combined noise‐ and toluene‐induced nephrotoxicity in Wistar rats.
Takoua Ben Attia, Mabrouk Horchani, Mariem Salhi, Zeineb Dhifallah, Meriem Ksentini, Hichem Ben Jannet, Abada Mhamdi   +6 more
wiley   +1 more source

Clonal Composition of Human Adrenocortical Neoplasms [PDF]

, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms are still not understood. Tumor formation may be the result of spontaneous transformation of adrenocortical cells by somatic mutations.
Abdelhamid, S., Allolio, B., Beuschlein, Felix, Chrousos, G. P., Jaursch-Hancke, C., Karl, M., Reincke, Martin, Travis, W.   +7 more
core  

Ontogeny of RSPO1, FOXL2, and RUNX1 during ovarian differentiation in the marsupial tammar wallaby

Developmental Dynamics, EarlyView.
Abstract Background RSPO1 and FOXL2 are female sex‐determining genes involved in the differentiation and organization of the ovary in some eutherian mammals. Mutations or loss of function of these genes are associated with partial to full sex reversal in mice, humans, and goats.
Monika R. Paranjpe, Yu Chen, Geoff Shaw, Marilyn B. Renfree   +3 more
wiley   +1 more source

Structure of the TPR Domain of AIP: Lack of Client Protein Interaction with the C-Terminal alpha-7 Helix of the TPR Domain of AIP Is Sufficient for Pituitary Adenoma Predisposition [PDF]

, 2012
PMCID: PMC3534021This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Laenger, A Puga, A Raitila, AF Daly, AF Daly, AJ Perry, AP Heaney, B Bukau, B Panaretou, BD Hollingshead, C Prodromou, C Prodromou, C Scheufler, CA Leontiou, Chrisostomos Prodromou, CM Greiser, D Spengler, DR Bell, E Heliovaara, EB Krissinel, F Glaser, G Huang, G Siligardi, G Trivellin, GB Bolger, Giampaolo Trivellin, Giorgio Colombo, H Ashkenazy, HS Chahal, HS Chahal, HS Chahal, HS Feigelson, I Persson, IW Davis, JL Marlowe, LA Carver, LA Carver, Laura C. Hernández-Ramírez, LH Pearl, Lihong Zhou, M Fujimoto, M Landau, M Linnert, M Yano, M Zhang, MP Mayer, Márta Korbonits, N Kuzhandaivelu, O Vierimaa, P Emsley, P Pocar, PH Pang, PV Afonine, Q Zeng, Rhodri M. L. Morgan, S Igreja, S Safe, S. Mark Roe, SK de Oliveira, SK de Oliveira, SK Kolluri, W Cai, Z Ozfirat   +62 more
core   +3 more sources

Pituitary tumors contain a side population with tumor stem cell-associated characteristics.

Endocrine-Related Cancer, 2015
Pituitary adenomas cause significant endocrine and mass-related morbidity. Little is known about the mechanisms that underlie pituitary tumor pathogenesis.
Freya Mertens, L. Gremeaux, Jiang-hai Chen, Q. Fu, C. Willems, Heleen Roose, O. Govaere, T. Roskams, C. Cristina, D. Becu-Villalobos, M. Jorissen, V. Poorten, M. Bex, Johannes van Loon, H. Vankelecom   +14 more
semanticscholar   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Thyroxine-binding globulin: investigation of microheterogeneity [PDF]

, 1981
Preparations of T4-binding globulin (TBG) from human serum was performed using only two affinity chromatography steps. Purity of the protein was demonstrated by a single band in overloaded disc and sodium dodecyl sulfate electrophoresis, equimolar ...
Gärtner, Roland, Henze, R., Horn, K., Pickardt, C. R., Scriba, Peter Christian   +4 more
core   +1 more source