Results 141 to 150 of about 3,206,200 (405)

Gene signatures and prognostic analyses of the Tob/BTG pituitary tumor-transforming gene (PTTG) family in clinical breast cancer patients [PDF]

open access: gold, 2020
Chung-Che Wu   +6 more
openalex   +1 more source

Drugs in focus: Budesonide and its role in paediatric gastrointestinal disorders

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Budesonide is a glucocorticoid with strong topical anti‐inflammatory properties and minimal systemic effects due to extensive first‐pass hepatic metabolism. It is designed for targeted delivery within the gastrointestinal (GI) tract and is available in oral and rectal formulations.
Sohail Aziz   +11 more
wiley   +1 more source

Impact of Baseline Nutritional Status, Psychological Health, Fatigue, and Insomnia on Outcomes of Immune Checkpoint Inhibitors in Advanced Non‐Small Cell Lung Cancer: A Retrospective Cohort Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study investigated the impact of pretreatment nutritional status, psychological health, fatigue, and insomnia on outcomes of immune checkpoint inhibitors (ICIs) monotherapy in patients with advanced non‐small cell lung cancer (NSCLC). A total of 80 patients with stage IV NSCLC were enrolled.
Yu‐Xuan Zhu   +2 more
wiley   +1 more source

Harnessing Gut Microbiome–Brain–Liver Crosstalk: Novel Therapeutic Strategies for Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesMedicine Bulletin, EarlyView.
This review reveals the complex mechanisms by which the brain–gut–liver axis (particularly the gut microbiota and its metabolites) drives MASLD, highlighting the therapeutic value of using phages to target and eliminate pathogenic bacteria and their metabolic products.
Xingtao Zhao   +7 more
wiley   +1 more source

Comparative Analysis of the Incidence, Prevalence, and Survival of 8 Types of Parkinsonism in a Population‐Based Study with 367 Million Person Years of Observation over 21 Years

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Findings are contradictory regarding changes in the incidence and prevalence of Parkinson's disease (PD) over time; data for other parkinsonian disorders are rare. Objectives To analyze temporal trends in the incidence and prevalence of eight parkinsonisms (PD, MSA, PSP, CBS, DLB, vascular parkinsonism, drug‐induced parkinsonism ...
Sacha E. Gandhi   +7 more
wiley   +1 more source

Disparities in Growth Hormone Deficiency Screening, Evaluation, Diagnosis, and Treatment Among At‐Risk Childhood Cancer Survivors in the US

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Minoritized childhood cancer survivors (CCS) may encounter barriers to timely late effects surveillance. We aimed to evaluate clinical and demographic differences in the likelihood of, and timing to, growth hormone deficiency (GHD) screening, evaluation, diagnosis, and treatment among at‐risk CCS treated with radiation therapy (RT).
Fulfilled Ighalo   +7 more
wiley   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

open access: yesPediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu   +4 more
wiley   +1 more source

Endocrinology of the hypothalamus and the pituitary gland [PDF]

open access: yes, 1973
Kuhlendahl, Hans   +1 more
core   +1 more source

Management of Noncatastrophic Internal Carotid Artery Injury in Endoscopic Skull Base Surgery. [PDF]

open access: yes, 2019
Arterial injuries are the most feared complication of endoscopic skull base surgery. During resection of the middle fossa component of a large ventral skull base chondrosarcoma, arterial bleeding was encountered near the right internal carotid artery ...
El-Sayed, Ivan H   +3 more
core  

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