Results 151 to 160 of about 3,101,103 (310)
Local Growth Hormone Facilitates Aging of the Colon Epithelial Microenvironment
Local growth hormone (GH) is expressed and secreted by senescent cells in the aging human colon. GH triggers epithelial‐to‐mesenchymal transition and activates colon cell motility by regulating extracellular matrix proteins, inducing cytoskeleton rearrangement and altering cell motility protein phosphorylation.
Vera Chesnokova+8 more
wiley +1 more source
TSP50 expression declines in the hippocampus of aged humans and mice. TSP50 deficiency in NSCs accelerates mouse aging, causing cognitive impairments and neuroinflammation. Restoring gut microbiota via FMT and TSP50 overexpression alleviates these phenotypes. Our study shows TSP50's critical role in aging and gut microbiota as a key mediator.
Xiaoli Li+15 more
wiley +1 more source
Editorial: Recent advances in the mechanism and treatment of pituitary tumors. [PDF]
Shi W, Liu Q, Jia F, Wang X.
europepmc +1 more source
Clinical Features, Diagnosis, and Treatment of Metastatic Pituitary Tumors
Akio Morita+3 more
openalex +2 more sources
Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas+6 more
wiley +1 more source
Targeting Autophagy for Pituitary Tumors. [PDF]
Yin E, Satou M, Tateno T.
europepmc +1 more source
Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret+5 more
wiley +1 more source