Results 1 to 10 of about 6,021 (252)

Tofacitinib for Pityriasis Rubra Pilaris: A Case Report [PDF]

Clinical, Cosmetic and Investigational Dermatology
Hongyan Tan, Bin Zhang, Xiawei Kang, Lvyao Wang, Xiao Qiu, Xiangyu Hu Department of Dermatology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, 400011, People’s Republic of ChinaCorrespondence: Xiangyu Hu, Email 369930758@qq.comPurpose ...
Tan H, Zhang B, Kang X, Wang L, Qiu X, Hu X   +5 more
doaj   +6 more sources

Oral Alitretinoin for the Treatment of Recalcitrant Pityriasis Rubra Pilaris [PDF]

Case Reports in Dermatology, 2011
Treatment of pityriasis rubra pilaris is still challenging. We here present a 74-year-old woman who had not experienced stable remission of her skin symptoms during prior treatments including topical and systemic corticosteroids, phototherapy, orally ...
Laurenz Schmitt, Oliver Inhoff, Edgar Dippel   +2 more
doaj   +6 more sources

Pityriasis rubra pilaris partially responsive to treatment with upadacitinib: A case report [PDF]

SAGE Open Medical Case Reports, 2023
Pityriasis rubra pilaris is a rare inflammatory dermatosis characterized by orange-red confluent plaques, hyperkeratotic follicular papules, palmoplantar keratoderma, and, in some cases, erythroderma.
Mysa Saad, Alison Spurr, Jennifer Lipson
doaj   +3 more sources

Efficacy and safety of small molecule drugs in the treatment of pityriasis rubra pilaris—A systematic review [PDF]

Frontiers in Medicine
BackgroundPityriasis rubra pilaris is a chronic, scaly, keratotic skin disease, mainly manifested as scaly plaques and keratinized hair follicles. This condition significantly impacts the patient’s quality of life and is considered one of the intractable
Xiaofang Zhang, Kebo Wei, Hongxia Song, Xi Chen, Jiao Yang, Jianmei Zhao, Yugu Jiang, Xin He   +7 more
doaj   +5 more sources

Targeting IL-1 controls refractory pityriasis rubra pilaris. [PDF]

Sci Adv
Pityriasis rubra pilaris (PRP) is a rare inflammatory skin disease with a poorly understood pathogenesis. Through a molecularly driven precision medicine approach and an extensive mechanistic pathway analysis in PRP skin samples, compared to psoriasis ...
Schmauch E, Severin Y, Xing X, Mangold A, Conrad C, Johansen P, Kahlenberg JM, Mellett M, Navarini A, Nobbe S, Sarkar MK, Satyam A, Tsoi LC, French LE, Nilsson J, Linna-Kuosmanen S, Kaikkonen MU, Snijder B, Kellis M, Gudjonsson JE, Tsokos GC, Contassot E, Kolios AGA.   +22 more
europepmc   +4 more sources

Updates on Pityriasis Rubra Pilaris: A Scoping Review. [PDF]

J Cutan Med Surg
Pityriasis rubra pilaris (PRP) is a rare, inflammatory papulosquamous skin disease with unknown exact etiology. Historically, PRP has been challenging to diagnose, especially during the acute phase, and to treat, due to its unclear pathogenesis.
Zhou T, Al Muqrin A, Abu-Hilal M.
europepmc   +4 more sources

Loss-of-function mutations in Keratin 32 gene disrupt skin immune homeostasis in pityriasis rubra pilaris. [PDF]

Nat Commun
Pityriasis rubra pilaris (PRP) is an inflammatory papulosquamous dermatosis, characterized by hyperkeratotic follicular papules and erythematous desquamative plaques. The precise pathogenic mechanism underlying PRP remains incompletely understood. Herein,
Shi P, Chen W, Lyu X, Wang Z, Li W, Jia F, Zheng C, Liu T, Wang C, Zhang Y, Mi Z, Sun Y, Chen X, Chen S, Zhou G, Liu Y, Lin Y, Bai F, Sun Q, Ogese MO, Yu Q, Liu J, Liu H, Zhang F.   +23 more
europepmc   +4 more sources

Emerging Role of Biologic Drugs Targeting IL-17 and IL-23: Pityriasis Rubra Pilaris. [PDF]

Life (Basel)
Pityriasis rubra pilaris (PRP) is a rare, papulosquamous, inflammatory skin disease. PRP represents a therapeutic challenge. The rarity of this disease and its possible spontaneous remission makes the conduction and interpretation of therapeutic studies ...
Potestio L, D'Agostino M, Portarapillo A, Esposito V, Tommasino N, Salsano A, Guerriero L, Martora F, Megna M.   +8 more
europepmc   +3 more sources

Refractory pityriasis rubra pilaris treated with upadacitinib [PDF]

JAAD Case Reports, 2023
Eingun James Song, MD, Miriam A. Al-Saedy, BS, Nicole Bouché, BS   +2 more
doaj   +3 more sources

Pityriasis rubra pilaris presenting with an abnormal autoimmune profile: two case reports [PDF]

Journal of Medical Case Reports, 2009
Introduction Pityriasis rubra pilaris is an uncommon inflammatory and hyperproliferative dermatosis of juvenile or adult onset. The etiology of the disease is still unknown.
Gregoriou Stamatis, Chiolou Zoe, Stefanaki Christina, Zakopoulou Niki, Rigopoulos Dimitrios, Kontochristopoulos George   +5 more
doaj   +4 more sources