Results 81 to 90 of about 380,958 (305)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Fusion of Weighted Mean Reconstruction and SVMCK for Hyperspectral Image Classification

open access: yesIEEE Access, 2018
Conventional classifiers treat hyperspectral image (HSI) as a list of spectral measurements without considering the spatial relationship between pixels. Therefore, these methods discard the information associated with spatial correlations among distinct ...
Hong Huang   +3 more
doaj   +1 more source

Comparison of detection results when changing image size from 256 pixels to 1100 pixels.

open access: yes, 2021
Comparison of detection results when changing image size from 256 pixels to 1100 pixels.
Leonardo Vanneschi (11767436)   +6 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

PIXEL 2010 – A Résumé [PDF]

open access: yesNuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2011
The Pixel 2010 conference focused on semiconductor pixel detectors for particle tracking/vertexing as well as for imaging, in particular for synchrotron light sources and XFELs. The big LHC hybrid pixel detectors have impressively started showing their capabilities.
openaire   +3 more sources

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Surface projection for mixed pixel restoration

open access: yes, 2009
Amplitude modulated full-field range-imagers are measurement devices that determine the range to an object simultaneously for each pixel in the scene, but due to the nature of this operation, they commonly suffer from the significant problem of mixed ...
Michael J. Cree   +7 more
core   +1 more source

Rolling Pixels

open access: yes, 2020
This article introduces Rolling Pixels, that are essentially robotic Steinmetz solids, for constructing frame-by-frame physical animations. As a bicylinder-shaped Rolling Pixel rolls back and forth or left and right, the shape and color of the top view ...
Hyunjung Kim   +5 more
core   +1 more source

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