Results 231 to 240 of about 383,310 (333)

Effect of the gut microbiota metabolite phenylacetylglycine on cardiac Ca²⁺ signaling. [PDF]

Biophys Rep (N Y)
Bovo E, Zima AV.
europepmc   +1 more source

A Mononuclear Ruthenium(V)‐Imido Complex With Hydrogen Bonding in the Second Coordination Sphere Forming Aziridines Without N‐Substituents From Alkenes in Water

Angewandte Chemie International Edition, EarlyView.
This study employs a RuV═NH complex with hydrogen‐bonding (HB) sites in the SCS to afford non‐N‐substituted aziridines selectively. Nitrogen‐atom transfer occurs from the RuV═NH complex to alkenes in water to produce aziridine derivatives in high yields.
Tomoya Ishizuka, Chisato Ogawa, Yoshihito Shiota, Shunsuke Nozawa, Hiroaki Kotani, Shin‐ichi Adachi, Kazunari Yoshizawa, Takahiko Kojima   +7 more
wiley   +1 more source

Phosphorylation deficient inducible cAMP early repressor (ICER) modulates tumorigenesis and survival in a transgenic zebrafish (Danio rerio) model of melanoma

Biology Open
Justin Wheelan, Melissa Spigelman, Angelo Cirinelli, James Reilly, Carlos A. Molina   +4 more
doaj   +1 more source

Severe Recurrent Polyhydramnios as a Prenatal Signal of MAGED2-Related Bartter Syndrome: A Clinical Perspective. [PDF]

Clin Med Insights Pediatr
Engel O, Eisenberg H, Barda J, Yosovich K, Kaidar M, Gindes L, Banne E.   +6 more
europepmc   +1 more source

Inosine‐Triphosphate‐Pyrophosphatase Activity as a Potential Predictor of Methotrexate Remission in Juvenile Idiopathic Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Methotrexate (MTX) is the first‐line therapy for juvenile idiopathic arthritis (JIA), but up to 40% of patients do not respond to it. Low inosine triphosphate pyrophosphatase (ITPA) activity has been associated with reduced clinical remission. We investigated the role and underlying mechanisms of ITPA in vitro. Methods ITPA enzymatic activity
Sofia Sindici Forgiarini, Marianna Lucafò, Debora Curci, Davide Selvestrel, Valentina Moressa, Sofia Pagarin, Barbara Bellich, Martina Franzin, Alberto Tommasini, Mara L. Becker, Laura B. Ramsey, Susan D. Thompson, Carl D. Langefeld, Federica Corba, Edoardo Marrani, Gabriele Simonini, Gabriele Stocco, Giuliana Decorti, Andrea Taddio, Serena Pastore   +19 more
wiley   +1 more source

TrIPP: a trajectory iterative pKa predictor. [PDF]

Bioinformatics
Matsingos C, Man KF, Fornili A.
europepmc   +1 more source

A systematic scoping review of metrics utilized to measure antibiotic consumption in hospital settings

British Journal of Clinical Pharmacology, EarlyView.
Abstract Antimicrobial stewardship (AMS) programs were introduced to promote the judicious use of antimicrobials and to combat antimicrobial resistance. Quantifying antibiotic consumption is an important part of AMS initiatives to achieve these objectives.
Marjan Kandimahforoujaki, Kiplin A. Patanwala, Jan‐Willem C. Alffenaar, Asad E. Patanwala   +3 more
wiley   +1 more source

Bile Canalicular Bitter Taste Receptors Inhibit β-Adrenergic Receptor-Induced Lipolysis in Steatotic Hepatocytes. [PDF]

Int J Mol Sci
Xue YB, Gong SM, Peng YY, Yu D, Zhou R, Huang L.   +5 more
europepmc   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Correlated Molecular Orbital Theory Predictions of Hydrogen-Containing Halomethane Thermochemistry: Heats of Formation, C-H Bond Dissociation Energies, and p<i>K</i>_a Values. [PDF]

J Phys Chem A
Andress TD, Seely C, Miele M, Castoldi L, Pace V, Dixon DA.   +5 more
europepmc   +1 more source