Results 261 to 270 of about 383,310 (333)

HHEX-PRKAR2B axis-mediated PKA activation drives glucose metabolism-dependent progression of pancreatic ductal adenocarcinoma. [PDF]

iScience
Wen J, Li Q, Xu S, Lu W, Wu F, Lou J, Wang L.   +6 more
europepmc   +1 more source

Dissection of Gαs and Hedgehog Signaling Cross-talk Reveals Therapeutic Opportunities to Target Hedgehog-Dependent Tumors. [PDF]

Cancer Res
Krantz S, Bell BA, Lund K, Salinas Parra N, Ng Y, De Oliveira Rosa N, Mukhopadhyay S, St Croix B, Sarin KY, Weigert R, Raimondi F, Iglesias-Bartolome R.   +11 more
europepmc   +1 more source

Structural and Functional Regulation of RyR2 in Cardiac Calcium Handling and Arrhythmogenesis. [PDF]

Biomedicines
Gao K, Wang W, Ling Y, Li B, Xing C, Li N, Yin X, Tao L, Li X, Qiu J, Wang X, Wei J.   +11 more
europepmc   +1 more source

Upstream CB1R Regulation of β-Adrenergic Memory Consolidation. [PDF]

Hippocampus
Rossato JI, Ribeiro L, Lima-Silva T, Araujo R, Orvate R, Azevedo AL, Bevilaqua Cammarota N, Baracho AL, Carneiro L, Cammarota M.   +9 more
europepmc   +1 more source

Graph-Based Deep Learning Models for Predicting p<i>K</i>_a Values of Protein-Ionizable Residues via Physically Inspired Feature Engineering. [PDF]

J Chem Inf Model
Song Z, Wang R, Jiao X, Huang Z.
europepmc   +1 more source

The PKA/MBD2 Axis Transcriptionally Represses INPP5A to Modulate PI3K/Akt Signaling and Accelerate Pituitary Tumorigenesis. [PDF]

CNS Neurosci Ther
Jiang Q, Wang Y, Wang Z, Wang Q, Li S, Xu L, Zhang Z, Tan Z, Zhang H, Shu K, Lei T, Huang Y, Lei Z.   +12 more
europepmc   +1 more source

The expanding landscape of the glucagon signaling network: mechanisms and outcomes.

Endocrinology
Foollee A, Wu Y, Rusu PM, Rose AJ.
europepmc   +1 more source

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A Structural Comparison of Inhibitor Binding to PKB, PKA and PKA-PKB Chimera

Journal of Molecular Biology, 2007
Although the crystal structure of the anti-cancer target protein kinase B (PKBbeta/Akt-2) has been useful in guiding inhibitor design, the closely related kinase PKA has generally been used as a structural mimic due to its facile crystallization with a range of ligands.
Brent Graham, Ian Collins, Steven J Woodhead   +2 more
exaly   +3 more sources