Differential Regulation of PKM2, AMPK, and mTOR in Response to Insulin and Dietary Management. [PDF]
Broberg E+6 more
europepmc +1 more source
The glycolytic enzyme PKM2 regulates inflammatory osteoclastogenesis by modulating STAT3 phosphorylation. [PDF]
Li M+6 more
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Targeting stem-property and vasculogenic mimicry for sensitizing paclitaxel therapy of triple-negative breast cancer by biomimetic codelivery. [PDF]
Wu S+7 more
europepmc +1 more source
The predictive function of miR-122-5p and its action mechanism by regulating PKM2 in metabolic syndrome. [PDF]
Zhou X, Wu R, Tang G, Shen T, Li W.
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Circular RNA hsa_circ_103089 modulates metabolic glycolysis and influences migration, invasion, and cisplatin sensitivity in non-small cell lung cancer cells via the miR-876-5p/EGFR axis. [PDF]
Zhou Y+8 more
europepmc +1 more source
A novel pathway for stemness propagation and chemoresistance in non-small cell lung cancer via phosphorylated PKM2-loaded small extracellular vesicles. [PDF]
Wang J+16 more
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RETRACTION: PCAT-1' s Role in Wound Healing Impairment: Mitochondrial Dysfunction and Bone Marrow Stem Cell Differentiation Inhibition via PKM2/β-Catenin Pathway and its Impact on Implant Osseo-Integration. [PDF]
europepmc +1 more source
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Key Points: 1. Platelet activation increases PKM2 dimer formation, which modulates platelet functions and arterial thrombosis. 2. PKM2 regulates PI3Kmediated Akt and GSK3 signaling.
Nayak, Manasa+8 more
openaire +1 more source