Results 271 to 280 of about 24,169 (302)

PKM2 controls cochlear development through lactate-dependent transcriptional regulation. [PDF]

Proc Natl Acad Sci U S A
Wu M, Jia G, Liu Y, Lou Y, Li Y, Xia M, Li H, Li W.   +7 more
europepmc   +1 more source

The TRPV1-PKM2-SREBP1 axis maintains microglial lipid homeostasis in Alzheimer's disease. [PDF]

Cell Death Dis
Sha X, Lin J, Wu K, Lu J, Yu Z.
europepmc   +1 more source

GMRSP encoded by lncRNA H19 regulates metabolic reprogramming and alleviates aortic dissection. [PDF]

Nat Commun
Wang J, Liu J, Yang F, Sun Y, Chen J, Liu J, Sun T, Fan R, Pei F, Luo S, Li J, Luo J.   +11 more
europepmc   +1 more source

The role and mechanism of aerobic glycolysis in nasopharyngeal carcinoma. [PDF]

PeerJ
Pan Z, Liu Y, Li H, Qiu H, Zhang P, Li Z, Wang X, Tian Y, Feng Z, Zhu S, Wang X.   +10 more
europepmc   +1 more source

TIPE drives a cancer stem-like phenotype by promoting glycolysis via PKM2/HIF-1α axis in melanoma. [PDF]

Elife
Tian M, Yang L, Zhao Z, Li J, Wang L, Yin Q, Hu W, Lou Y, Du J, Zhao P.   +9 more
europepmc   +1 more source

PKM2-mediated collagen XVII expression is critical for wound repair. [PDF]

JCI Insight
Liu Y, Ho C, Wen D, Sun J, Liu Y, Li Q, Zhang Y, Gao Y.   +7 more
europepmc   +1 more source

Exploring the Link Between Noncoding RNAs and Glycolysis in Colorectal Cancer. [PDF]

J Cell Mol Med
Xu L, Shen Y, Zhang C, Shi T, Sheng X.
europepmc   +1 more source

Metabolic reprogramming of macrophages by PKM2 promotes IL-10 production via adenosine.

Cell Rep
Toller-Kawahisa JE, Viacava PR, Palsson-McDermott EM, Nascimento DC, Cervantes-Silva MP, O'Carroll SM, Zotta A, Damasceno LEA, Públio GA, Forti P, Luiz JPM, Silva de Melo BM, Martins TV, Faça VM, Curtis A, Cunha TM, Cunha FQ, O'Neill LAJ, Alves-Filho JC.   +18 more
europepmc   +1 more source

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PKM2 Blood.pdf

2023
Key Points: 1. Platelet activation increases PKM2 dimer formation, which modulates platelet functions and arterial thrombosis. 2. PKM2 regulates PI3Kmediated Akt and GSK3 signaling.
Nayak, Manasa, Ghatge, Madankumar, Flora, Gagan D., Dhanesha, Nirav, Jain, Manish, Markan, Kathleen R., Potthoff, Matthew J., R. Lentz, Steven, Chauhan, Anil K.   +8 more
openaire   +1 more source

Sarsasapogenin, a principal active component absorbed into blood of total saponins of Anemarrhena, attenuates proliferation and invasion in rheumatoid arthritis fibroblast‐like synoviocytes through downregulating PKM2 inhibited pathological glycolysis

Phytotherapy Research, 2023
Increased glycolytic in fibroblast‐like synoviocytes (FLS) of rheumatoid arthritis (RA) not only contributes to early‐stage disease pathogenesis but leads to sustained proliferation of FLS.
Yuan Dai, Panwang Liu, Wen Wen, Ping Li, Chen Yang, Ping Wang, Shijun Xu   +6 more
semanticscholar   +1 more source