Results 11 to 20 of about 11,988 (216)
Hepatology, EarlyView., 2022 Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan +22 more
wiley +1 more source
Allelic phenotype prediction of phenylketonuria based on the machine learning method
Human Genomics, 2023 Background Phenylketonuria (PKU) is caused by mutations in the phenylalanine hydroxylase (PAH) gene. Our study aimed to predict the phenotype using the allelic genotype.
Yang Fang +10 more
doaj +1 more source
The Adult Phenylketonuria (PKU) Gut Microbiome
Microorganisms, 2021 Phenylketonuria (PKU) is an inborn error of phenylalanine metabolism primarily treated through a phenylalanine-restrictive diet that is frequently supplemented with an amino acid formula to maintain proper nutrition.
Viviana J. Mancilla +3 more
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Dental Status and Periodontal Health of Patients with Phenylketonuria in Latvia
Acta Stomatologica Croatica, 2022 Objectives: Phenylketonuria (PKU) is an autosomal recessive inherited disorder of phenylalanine metabolism resulting from a deficiency of phenylalanine hydroxylase.
Iveta Abola +5 more
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Fenilcetonuria and hyperactivity: results in extremeños children
INFAD, 2015 Phenylketonuria (PKU) is a type of hyperphenylalaninemias, which are an inborn group of errors of the amino acid phenylalanine metabolism that are usually characterized by producing a severe mental retardation and even death if it is not treated properly.
Virgilio García Aparicio +1 more
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Comparison of IQ scores between children with phenylketonuria and healthy children referring to Besat Hospital in Sanandaj between 2017 and 2018 [PDF]
مجله علمی دانشگاه علوم پزشکی کردستان, 2019 Background and Aim: Phenylketonuria is a genetic and congenital metabolic disorder with autosomal recessive transmission. In this disease phenylalanine is not converted to tyrosine due to lack of phenylalanine hydroxylase enzyme which results in ...
Asadollah Fatholahpuor +3 more
doaj +1 more source
Journal of Orthopaedic Surgery and Research, 2020 Background Inflammation and apoptosis of chondrocytes are the pathological bases of osteoarthritis. Autophagy could alleviate the symptoms of inflammation and apoptosis. Previous study has shown that BCL2/adenovirus E1B 19 kDa protein-interacting protein
Zetao Ma +4 more
doaj +1 more source
Archives of Disease in Childhood, 2006 My name is Elizabeth Hooley and I am 13 years old. I have phenylketonuria (PKU) so cannot eat meat, fish, cheese, eggs, poultry, most dairy products, or anything else high in protein. Also, I cannot have any light, diet, or sugar-free drinks or food. I am allowed all fruits—but only one small banana a day.
openaire +3 more sources
Trends in Pediatrics, 2021 Objective: Diet is the main component in the treatment of classical phenylketonuria (PKU). Living in the same house as a PKU patient affects the lifestyle of family members in many ways.
Pelin Teke Kısa +6 more
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Nutrition and Dietary Supplements, 2021 Laurie Bernstein,1,2 Joyanna Hansen,3 Christian Kogelmann,4 Margret Ellerbrok,4 Maria Gizewska,5 Sommer Gaughan,6 Julio Cesar Rocha,7– 9 Amaya Belanger,10 Fran Rohr2 1Section of Clinical Genetics and Metabolism, Department of Pediatrics, University of ...
Bernstein L +8 more
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