Results 201 to 210 of about 135,494 (269)

Exposure to polylactic acid microplastics during puberty increases the risk of skeletal dysplasia by disrupting arachidonic acid metabolism in osteoblasts. [PDF]

Part Fibre Toxicol
Zhang Y, Cai Z, Luo X, Chen H, Zhang X, Pan C.   +5 more
europepmc   +1 more source

CHCHD10 Mitigates Alzheimer's Disease‐Related Phenotypes in Association With Epigenetic Remodeling in Directly Reprogrammed Neurons

Advanced Science, EarlyView.
CHCHD10 loss in Alzheimer's disease is associated with mitochondrial dysfunction, epigenomic disruption, and tau pathology. Restoration of CHCHD10 shifts DNA methylation toward a non‐disease state and reduces tau and amyloid pathology, with KATNAL2 acting as a downstream effector.
Teresa M. Thomas, Ching‐Yao Yang, Kexin Zhang, Liam Wetzel, Dina Bugybayeva, Julia Ferguson, Md Mahmudul Hasan, William Samsa, Nandita Patil, Anshul Dash, Tarini Gowda, Xiongwei Zhu, Feixiong Cheng, Tian Liu   +13 more
wiley   +1 more source

PLA/Collagen/Hydroxyapatite Ternary Biocomposites for Biodegradable Bone Screw Applications. [PDF]

Polymers (Basel)
Uzuner-Demir A, Yıldırım R, Koçoğlu H, Aydoğan-Gemici M, Ahi ZB, Arıcan F, Mert O, Özkoç G, Kodal M.   +8 more
europepmc   +1 more source

Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS) in Glioblastoma

Advanced Science, EarlyView.
ABSTRACT Glioblastoma (GBM) remains one of the most challenging brain malignancies due to the restrictive nature of the blood–brain barrier (BBB), which severely limits effective drug and gene delivery. To overcome this, we introduce Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS), a modular platform that enables safe ...
Gulsah Erel‐Akbaba, Jinyoung Park, Achal Duhoon, Cao Thuy Giang Nguyen, Nitu Bhaskar, Sumanta Kumar Karan, Hasan Akbaba, Parbeen Singh, Thi Bao Tram Tran, Yuhui Zhu, Zhiming Li, I'jaaz Muhammad, Xiaojun Zhang, Hoang Quan Truong, A. Daniel Davidar, Elizabeth Schmitzer, Vikas N. Vattipally, Angelica F. Lopez, Patrick Kramer, Victor M. Quiroz, Ben Bykov, Claire Hao, Amir Manbachi, Nicholas Theodore, Joshua C. Doloff, Thanh D. Nguyen   +25 more
wiley   +1 more source

Bio-Inspired 3D-Printed Polymeric Sheets for Orthoses: Predictive Modeling of Mechanical Integrity and Moisture Absorption. [PDF]

Biomimetics (Basel)
Devesa-Rey R, Arce E, Losada-Pérez S, Álvarez-Feijoo MÁ, Leirós-Rodríguez R.   +4 more
europepmc   +1 more source

Deep Learning Network‐Tailored Microenvironment Matching of 4D Bioprinting Bioactive Scaffolds for Bone Regeneration

Advanced Science, EarlyView.
A DLN dataset was built to analyze MABS composition versus in vitro/in vivo osteogenesis and angiogenesis. An MLP neural network, taking BG morphological parameters as input, extracts bioactive features from these datasets. A rabbit tibial defect model then validates 4D‐printed MABS for adaptability and bone regeneration in critical defects.
Xiongjie Liang, Yuechi Zhang, Weifeng Hu, Shiyan Lv, Fan Jia, Yan Zhang, Feng Wu, Changjiang Yang, Guanqi Zhen, Jinglong Yan, Xu Cui, Wei Zhao, Guanghua Chen   +12 more
wiley   +1 more source

Lean Mass Gains, Cardiac Remodeling, and Muscle Oxidative Changes With High-Dose Salbutamol During Resistance Training: A Randomized Controlled Trial. [PDF]

Scand J Med Sci Sports
Hostrup M, Jessen S, Tischer SG, Kalsen A, Hadad R, Bonde PL, Kreiberg M, Gad AS, Sajadieh A, Backer V, Bangsbo J, Rasmusen H.   +11 more
europepmc   +1 more source

Interplay between the Molecular Structure of Lignin and the Degradation Process of PLA/Lignin Materials. [PDF]

Biomacromolecules
Rodríguez PPI, Odelius K, Hakkarainen M.   +2 more
europepmc   +1 more source

A Composite Based on <i>L</i>-Polylactide with Cu or CuO Nanoparticles: Physical Properties and Biological Activity. [PDF]

Polymers (Basel)
Serov DA, Yanbaev FM, Burmistrov DE, Baimler IV, Liubimovskii SO, Kozlova LY, Popov IA, Gritsaeva AV, Fomina PA, Sizov LR, Kozlov VA, Kuzmin EV, Simakin AV, Astashev ME, Gudkov SV.   +14 more
europepmc   +1 more source