Results 81 to 90 of about 1,012,931 (308)

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Diseño de una formulación parenteral para la liberación prolongada de risperidona basada en un sistema de gelificación in situ

Revista Cubana de Investigaciones Biomédicas, 2019
Introducción: los sistemas de administración parenteral a base de formulaciones líquidas que gelifican in situ que forman implantes semisólidos de libración sostenida de fármacos después de la inyección, son muy atractivos por varias razones.
Carlos Julio Peniche, Hazel Peniche, Nancy Bada, Vivian Sáez, Niuris Acosta, Carlos Peniche Andrés Peniche   +5 more
doaj  

Stereocomplex formation in ABA triblock copolymers of poly(lactide) (A) and poly(ethylene glycol) (B) [PDF]

, 1995
Two series of triblock copolymers of poly(ethylene glycol) (PEG, number-average molecular weight [bar M ]n = 6000) and poly(L-lactide) (PLLA) or poly(D-lactide) (PDLA) were prepared by ring-opening polymerization of lactide initiated by PEG end groups ...
Ankone, Marc J.K., Dijkstra, Pieter J., Feijen, Jan, Stevels, Willem M.   +3 more
core   +2 more sources

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

Advanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens, Marco A. N. Domingos, Susan J. Kimber, Mahetab H. Amer   +5 more
wiley   +1 more source

Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation

Advanced Healthcare Materials, EarlyView.
This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad, Natasha K. Hunt, Srujan Singh, Kelly B. Seims, Yingjie Wu, E. Thomas Pashuck, Warren L. Grayson, Lesley W. Chow   +7 more
wiley   +1 more source

Biodegradable Polylactic Acid (PLA) Microstructures for Scaffold Applications [PDF]

, 2007
In this research, we present a simple and cost effective soft lithographic process to fabricate PLA scaffolds for tissue engineering. In which, the negative photoresist JSR THB-120N was spun on a glass subtract followed by conventional UV lithographic ...
Ho, K. -H., Hsueh, C. -C., Wang, G. -J.
core   +2 more sources

Copolymers of Poly(Butylene Trans‐1,4‐Cyclohexanedicarboxylate)/Pripol as New Biomaterial Platform for Small Diameter Vascular Graft

Advanced Healthcare Materials, EarlyView.
Electrospun tubular scaffolds from novel PBCE‐based copolyesters and blends were designed as candidates for small‐diameter vascular grafts. They combine defect‐free architecture, blood‐compatible surfaces, and mechanical properties comparable to native vessels.
Edoardo Bondi, Gabriele Obino, Giulia Guidotti, Alberto Sensini, Martijn van Griensven, Antonio Junior Lepedda, Nadia Lotti, Lorenzo Moroni   +7 more
wiley   +1 more source

Numerical study of impact energy absorption of auxetic structure [PDF]

MATEC Web of Conferences
3D printing technologies have helped researchers fabricate cellular structures and have lightweight and desirable mechanical properties. One such structure is called “auxetic” structures. “Auxetics” is the term used for structures that exhibit a negative
Govardhan Dussa, Rana Davinder, Jayahari L.   +2 more
doaj   +1 more source

Hydrothermally extracted nanohydroxyapatite from bovine bone as bioceramic and biofiller in bionanocomposite [PDF]

, 2019
Bones have an extraordinary capacity to restore and regenerate in case of minor injury. However, major injuries need orthopedic surgeries that required bone implant biomaterials.
Bano, Nazia
core  

Polylactic acid-nanocrystalline carbonated hydroxyapatite (PLA-cHAP) composite: preparation and surface topographical structuring with direct laser writing (DLW)

, 2016
The fabrication of polylactic acid (PLA)-carbonated hydroxyapatite (cHAP) composite material from synthesised phase pure nano-cHAP and melted PLA by mechanical mixing at 220-235{\deg}C has been developed in this study.
Alinauskas, Laurynas, Cicka, Roman, Drienovsky, Marian, Garskaite, Edita, Jonusauskas, Linas, Kareiva, Aivaras, Krajcovic, Jozef, Malinauskas, Mangirdas, Palcut, Marian, Stankeviciute, Zivile   +9 more
core   +1 more source