Results 121 to 130 of about 5,146,470 (314)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
PLACE Related Courses 2013-2014
, 2013 This document includes a complete list of all the related courses for the PLACE program at Linfield College from 2013 ...
PLACE
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Philosophy of Place: Finding Place and Self in the World
, 2022 This book discusses the philosophy of place and the implications for understanding ourselves authentically. It sets out to investigate this by providing a review of the phenomenological and humanistic views of place as background reading for the chapters
Crowden, Andrew, Gildersleeve, Matthew
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Festival place or place of festival? The role of place identity and attachment in the festival environment [PDF]
, 2014 This paper addresses place identity and attachment theory in the context of events. Viewing place as a symbolic part of the consumption process, a "Model of Festival Place" is developed.
Davis, Andrew, Martin, Andrew
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
PLACE: PRESENCE AS SECOND-PERSONAL SPACE
تأملات اخلاقی, 2020 The concept of place is ultimately a matter of ethical significance—of where something fits in a nexus or structure of meaning. Often this meaning is quite personal, involving a sense of presence we associate with a place.
Stephen Darwall
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Learning and Designing in a Virtual Place
, 2005 This paper reports on a study of the role of place in a virtual learning environment for digital media design. Using an immersive 3D Virtual World based on Active Worlds, we have created a virtual learning place for students in a Website Design course ...
S. Clark, M.Lou Maher
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