Results 61 to 70 of about 2,559,715 (278)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Public Initiatives in the Process of Establishment of Lithuania University
Lietuvos Istorijos Studijos, 2002 On the basis of Lithuanian public initiative and partly, financial support, higher courses were established in Kaunas on January 27, 1920. Higher courses were the very first step in the process of establishment of a higher school in Lithuania.
Virginija Jurėnienė
doaj +3 more sources
Gephyra, 2015 This paper deals with a mythological motif that we fairly frequently come across both in ancient literature and on coin images. Unfortunately, in the case of the coins the representation of this motif is mostly overlooked, not recognised or ...
Johannes Nollé
doaj +1 more source
Education for Democratic Citizenship: a review of research, policy and practice 1995-2005 [PDF]
, 2006 This paper provides a synthesis of the scholarly literature on education for democratic citizenship (EDC) in the school sector in England since 1995.
Osler, Audrey, Starkey, Hugh
core +3 more sources
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
The models of behaviour ofthe old generation historians in the presence of sovietization process
Lietuvos Istorijos Studijos, 2008 Ever since Lithuania has restored its independence in 1990, wide-ranging debates have been taking place on a question of individual and societal conformance, resistance, and collaboration during the times of Soviet occupation. This article inquires into
Aurimas Švedas
doaj +3 more sources
Constructing and Crossing Boundaries in a New (?) Europe [PDF]
, 2010 During the last two decades, discourses over the transition process shifted toward a theoretical diversity and a deeper understanding of ‘how modernity was reworked in postsocialist context’.
Nagy, Erika
core +2 more sources
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Jewish national autonomy in Lithuania in 1919-1926th
Lietuvos Istorijos Studijos, 1996 After World War I, the problems of the racial, linguistic, and religious minorities were brought to the attention of the Peace Conference of Paris. The Jewish community, through a special delegation, demanded the recognition of the Jews as a "national ...
Raimundas Valkauskas
doaj +3 more sources
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source