Results 71 to 80 of about 2,559,715 (278)
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Changes in the Ozone Content over Central Europe During Reversals of Stratospheric Circulation in Late Winter [PDF]
, 1984 A superposed epoch analysis during late winter zonal wind reversals was carried out from 18 year observation series (1963 to 1980) of the meridional geopotential height gradient in the 30 mb level (latitude mean) and of the ozone content over central ...
Entzian, G., Grasnick, K. H.
core +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Intereconomics, 2004 European regions increasingly compete to attract and retain residents, entrepreneurs and visitors. As the location choice of people is based more and more on such soft factors as an area’s image, most regions apply a strategy of “place marketing”. In this context, the Scandinavian Euregion of the Oresund is often highlighted as “best practice”.
openaire +2 more sources
Implementing place marketing policies in Europe [PDF]
International Journal of Sustainable Development and Planning, 2007 The purpose of this paper is to present a comparative evaluation of the implementation of place marketing policies in Europe. The cities that are examined are Glasgow, Lisbon and Prague. The evaluation uses data from particular promotion and strategic plans that each city planned in order to promote its image to the potential target markets effectively.
openaire +1 more source
The Economic Future of Europe [PDF]
After three years of near stagnation, the mood in Europe is definitely gloomy. Many doubt that the European model has a future. In this paper, I argue that things are not so bad, and there is room for optimism.
Olivier Blanchard
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Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
1. International Anarchy (1900-1918)
, 1958 It is probable that most people, if asked to list the characteristics of the Western World in this century, would place at or near the top of their list something about international rivalries.
Bloom, Robert L. +6 more
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Ukraine 2014 – The End of the Second European Belle Époque [PDF]
, 2016 This article is devoted to the roots of the developments that have taken place in Ukraine since Autumn 2013 and up to the Russian invasion. It stresses the historical differences between Ukraine and Russia, presents the international milieu of Ukrainian ...
Żurawski vel Grajewski, Przemysław
core +2 more sources